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    CALCRL calcitonin receptor like receptor [ Bos taurus (domestic cattle) ]

    Gene ID: 527140, updated on 4-Oct-2024

    Summary

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    Official Symbol
    CALCRLprovided by VGNC
    Official Full Name
    calcitonin receptor like receptorprovided by VGNC
    Primary source
    VGNC:VGNC:26705
    See related
    BGD:BT29805; Ensembl:ENSBTAG00000008483
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CALCRL in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (8891723..9020443)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342941 Neighboring gene peptidylprolyl isomerase-like 1 pseudogene Neighboring gene tissue factor pathway inhibitor Neighboring gene uncharacterized LOC132342942 Neighboring gene zinc finger SWIM-type containing 2 Neighboring gene family with sequence similarity 171 member B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Temporo-spatial expression of adrenomedullin and its receptors in the bovine placenta. Hayashi KG, et al. Reprod Biol Endocrinol, 2013 Jul 13. PMID 23849271, Free PMC Article
    2. Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking. Bomberger JM, et al. J Biol Chem, 2005 Mar 11. PMID 15613468
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC155061

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables adrenomedullin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcitonin gene-related peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcitonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcitonin gene-related peptide type 1 receptor
    Names
    CGRP type 1 receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102107.1 → NP_001095577.1  calcitonin gene-related peptide type 1 receptor precursor

      See identical proteins and their annotated locations for NP_001095577.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149184
      UniProtKB/Swiss-Prot
      A6QP74
      UniProtKB/TrEMBL
      G3X6P6
      Related
      ENSBTAP00000011169.6, ENSBTAT00000011169.6
      Conserved Domains (2) summary
      pfam02793
      Location:64 → 132
      HRM; Hormone receptor domain
      cd15274
      Location:140 → 403
      7tmB1_calcitonin_R; calcitonin receptor, member of the class B family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8891723..9020443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024975202.2 → XP_024830970.1  calcitonin gene-related peptide type 1 receptor isoform X1

      UniProtKB/Swiss-Prot
      A6QP74
      UniProtKB/TrEMBL
      G3X6P6
      Conserved Domains (2) summary
      pfam02793
      Location:64 → 132
      HRM; Hormone receptor domain
      cd15274
      Location:140 → 403
      7tmB1_calcitonin_R; calcitonin receptor, member of the class B family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6QP74.2 GenPept UniProtKB/Swiss-Prot:A6QP74

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.