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    KCNJ3 potassium inwardly rectifying channel subfamily J member 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 526088, updated on 4-Oct-2024

    Summary

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    Official Symbol
    KCNJ3provided by VGNC
    Official Full Name
    potassium inwardly rectifying channel subfamily J member 3provided by VGNC
    Primary source
    VGNC:VGNC:30461
    See related
    BGD:BT22778; Ensembl:ENSBTAG00000006159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GIRK-1
    Orthologs
    human mouse all
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    Genomic context

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    See KCNJ3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (41180769..41378908, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC132343575 Neighboring gene lysocardiolipin acyltransferase 1-like Neighboring gene polypeptide N-acetylgalactosaminyltransferase 13 Neighboring gene syndecan-3-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of native atrial G-protein-regulated inwardly rectifying K+ (GIRK4) channel homomultimers. Corey S, et al. J Biol Chem, 1998 Oct 16. PMID 9765280
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G-protein activated inward rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G protein-activated inward rectifier potassium channel 1
    Names
    inward rectifier K(+) channel Kir3.1
    potassium channel, inwardly rectifying subfamily J member 3
    potassium voltage-gated channel subfamily J member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192624.1 → NP_001179553.1  G protein-activated inward rectifier potassium channel 1

      See identical proteins and their annotated locations for NP_001179553.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000002
      UniProtKB/Swiss-Prot
      E1BNE9
      Related
      ENSBTAP00000008100.4, ENSBTAT00000008100.6
      Conserved Domains (2) summary
      pfam01007
      Location:47 → 187
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:194 → 364
      IRK_C; Inward rectifier potassium channel C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      41180769..41378908 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202435.5 → XP_005202492.1  G protein-activated inward rectifier potassium channel 1 isoform X1

      See identical proteins and their annotated locations for XP_005202492.1

      UniProtKB/TrEMBL
      A0AAA9RV79, A0AAA9TF66
      Related
      ENSBTAP00000076167.1, ENSBTAT00000123821.1
      Conserved Domains (2) summary
      pfam01007
      Location:47 → 187
      IRK; Inward rectifier potassium channel
      pfam17655
      Location:194 → 234
      IRK_C; Inward rectifier potassium channel C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1BNE9.1 GenPept UniProtKB/Swiss-Prot:E1BNE9

    Gene LinkOut

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