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    ARFRP1 ADP ribosylation factor related protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 525394, updated on 10-Oct-2024

    Summary

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    Official Symbol
    ARFRP1provided by VGNC
    Official Full Name
    ADP ribosylation factor related protein 1provided by VGNC
    Primary source
    VGNC:VGNC:26069
    See related
    BGD:BT10556; Ensembl:ENSBTAG00000007497
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ARFRP1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (54047388..54053621)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene SLC2A4 regulator Neighboring gene Lck interacting transmembrane adaptor 1 Neighboring gene zinc finger CCCH-type and G-patch domain containing Neighboring gene TNF receptor superfamily member 6b Neighboring gene regulator of telomere elongation helicase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Knockout of Arfrp1 leads to disruption of ARF-like1 (ARL1) targeting to the trans-Golgi in mouse embryos and HeLa cells. Zahn C, et al. Mol Membr Biol, 2006 Nov-Dec. PMID 17127620
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data suggest that lethality of Arfrp1 knockout embryos is due to a specific disruption of protein targeting, e.g., of ARL1 and Golgin-245, to the Golgi.
      Title: Knockout of Arfrp1 leads to disruption of ARF-like1 (ARL1) targeting to the trans-Golgi in mouse embryos and HeLa cells.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC134154

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-ribosylation factor-related protein 1
    Names
    ARF-related protein 1
    NP_001032696.1
    XP_024856398.1
    XP_024856399.1
    XP_059748608.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037607.1 → NP_001032696.1  ADP-ribosylation factor-related protein 1

      See identical proteins and their annotated locations for NP_001032696.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109550
      UniProtKB/Swiss-Prot
      Q32LJ2
      Conserved Domains (1) summary
      cd04160
      Location:19 → 186
      Arfrp1; Arf-related protein 1 (Arfrp1)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      54047388..54053621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025000630.2 → XP_024856398.1  ADP-ribosylation factor-related protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q32LJ2
      Conserved Domains (1) summary
      cd04160
      Location:19 → 186
      Arfrp1; Arf-related protein 1 (Arfrp1)

    2. XM_025000631.2 → XP_024856399.1  ADP-ribosylation factor-related protein 1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SB22
      Conserved Domains (1) summary
      cl38936
      Location:19 → 116
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    3. XM_059892625.1 → XP_059748608.1  ADP-ribosylation factor-related protein 1 isoform X2

      Related
      ENSBTAP00000082565.1, ENSBTAT00000126960.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32LJ2.1 GenPept UniProtKB/Swiss-Prot:Q32LJ2

    Gene LinkOut

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