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    MED27 mediator complex subunit 27 [ Bos taurus (domestic cattle) ]

    Gene ID: 525389, updated on 18-Aug-2024

    Summary

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    Official Symbol
    MED27provided by VGNC
    Official Full Name
    mediator complex subunit 27provided by VGNC
    Primary source
    VGNC:VGNC:31363
    See related
    BGD:BT21067; Ensembl:ENSBTAG00000000382
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    CRSP8
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (101917940..102165145, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene proline rich transmembrane protein 1B Neighboring gene Rap guanine nucleotide exchange factor 1 Neighboring gene uncharacterized LOC112448847 Neighboring gene uncharacterized LOC100847981 Neighboring gene netrin G2 Neighboring gene senataxin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC134262

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mediator of RNA polymerase II transcription subunit 27
    Names
    CRSP complex subunit 8
    cofactor required for Sp1 transcriptional activation subunit 8
    cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040546.2 → NP_001035636.1  mediator of RNA polymerase II transcription subunit 27

      See identical proteins and their annotated locations for NP_001035636.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109883
      UniProtKB/Swiss-Prot
      Q2TBN7
      UniProtKB/TrEMBL
      A0AAA9TY95
      Related
      ENSBTAP00000075882.1, ENSBTAT00000100749.1
      Conserved Domains (1) summary
      pfam11571
      Location:228 → 309
      Med27; Mediator complex subunit 27

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      101917940..102165145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010810432.4 → XP_010808734.1  mediator of RNA polymerase II transcription subunit 27 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TY95
      Related
      ENSBTAP00000102479.1, ENSBTAT00000107920.1

    2. XM_024998766.2 → XP_024854534.1  mediator of RNA polymerase II transcription subunit 27 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TS20, A0AAA9TY95
      Related
      ENSBTAP00000101175.1, ENSBTAT00000087951.1
      Conserved Domains (1) summary
      pfam11571
      Location:226 → 295
      Med27; Mediator complex subunit 27

    3. XM_005213279.5 → XP_005213336.1  mediator of RNA polymerase II transcription subunit 27 isoform X2

      UniProtKB/TrEMBL
      A0AAF6YGV8
      Conserved Domains (1) summary
      pfam11571
      Location:228 → 280
      Med27; Mediator complex subunit 27
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TBN7.1 GenPept UniProtKB/Swiss-Prot:Q2TBN7

    Gene LinkOut

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