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    SC5D sterol-C5-desaturase [ Bos taurus (domestic cattle) ]

    Gene ID: 525154, updated on 4-Oct-2024

    Summary

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    Official Symbol
    SC5Dprovided by VGNC
    Official Full Name
    sterol-C5-desaturaseprovided by VGNC
    Primary source
    VGNC:VGNC:34312
    See related
    BGD:BT25486; Ensembl:ENSBTAG00000019246
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SC5DL
    Orthologs
    human mouse all
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    Genomic context

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    See SC5D in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (31876177..31888129)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene tectorin alpha Neighboring gene uncharacterized LOC104974222 Neighboring gene uncharacterized LOC132342321 Neighboring gene essential MCU regulator, mitochondrial-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC127185

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol biosynthetic process via lathosterol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lathosterol oxidase
    Names
    sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
    sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like
    NP_001030433.1
    XP_005216026.2
    XP_005216027.1
    XP_005216028.1
    XP_024831062.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035356.1 → NP_001030433.1  lathosterol oxidase

      See identical proteins and their annotated locations for NP_001030433.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103338
      UniProtKB/TrEMBL
      Q3SYX8
      Conserved Domains (2) summary
      COG3000
      Location:40 → 191
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
      pfam04116
      Location:123 → 190
      FA_hydroxylase; Fatty acid hydroxylase superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      31876177..31888129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215970.5 → XP_005216027.1  lathosterol oxidase isoform X1

      See identical proteins and their annotated locations for XP_005216027.1

      UniProtKB/TrEMBL
      A0A3Q1MF09
      Conserved Domains (1) summary
      COG3000
      Location:40 → 257
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

    2. XM_005215969.5 → XP_005216026.2  lathosterol oxidase isoform X1

      See identical proteins and their annotated locations for XP_005216026.2

      UniProtKB/TrEMBL
      A0A3Q1MF09
      Related
      ENSBTAP00000072762.2, ENSBTAT00000072112.2
      Conserved Domains (1) summary
      COG3000
      Location:40 → 257
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

    3. XM_005215971.5 → XP_005216028.1  lathosterol oxidase isoform X1

      See identical proteins and their annotated locations for XP_005216028.1

      UniProtKB/TrEMBL
      A0A3Q1MF09
      Conserved Domains (1) summary
      COG3000
      Location:40 → 257
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]

    4. XM_024975294.2 → XP_024831062.1  lathosterol oxidase isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MF09
      Conserved Domains (1) summary
      COG3000
      Location:40 → 257
      ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    Nucleotide Protein Strain
    Heading Accession and Version

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