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    UBR1 ubiquitin protein ligase E3 component n-recognin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 522464, updated on 10-Oct-2024

    Summary

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    Official Symbol
    UBR1provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 1provided by VGNC
    Primary source
    VGNC:VGNC:36616
    See related
    BGD:BT28690; Ensembl:ENSBTAG00000021087
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See UBR1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    47
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (38181492..38333756, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene tau tubulin kinase 2 Neighboring gene large ribosomal subunit protein eL27-like Neighboring gene small ribosomal subunit protein eS6-like Neighboring gene uncharacterized LOC132346298 Neighboring gene large ribosomal subunit protein eL32-like Neighboring gene transmembrane protein 62 Neighboring gene cyclin D1 binding protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase UBR1
    NP_001192826.1
    XP_059746412.1
    XP_059746413.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205897.1 → NP_001192826.1  E3 ubiquitin-protein ligase UBR1

      See identical proteins and their annotated locations for NP_001192826.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000010
      UniProtKB/TrEMBL
      A0AAA9SPQ7, E1BIW0
      Related
      ENSBTAP00000028086.5, ENSBTAT00000028086.5
      Conserved Domains (2) summary
      pfam02207
      Location:99 → 166
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam02617
      Location:221 → 301
      ClpS; ATP-dependent Clp protease adaptor protein ClpS

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      38181492..38333756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059890429.1 → XP_059746412.1  E3 ubiquitin-protein ligase UBR1 isoform X1

      Related
      ENSBTAP00000085918.1, ENSBTAT00000090499.1

    2. XM_059890430.1 → XP_059746413.1  E3 ubiquitin-protein ligase UBR1 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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