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    AGXT2 alanine--glyoxylate aminotransferase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 521553, updated on 4-Oct-2024

    Summary

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    Gene symbol
    AGXT2
    Gene description
    alanine--glyoxylate aminotransferase 2
    See related
    BGD:BT29209; Ensembl:ENSBTAG00000007690
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See AGXT2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (39119608..39162313)

    Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343187 Neighboring gene prolactin receptor Neighboring gene transfer RNA tyrosine (anticodon AUA) Neighboring gene uncharacterized LOC132343238 Neighboring gene DnaJ heat shock protein family (Hsp40) member C21 Neighboring gene biogenesis of ribosomes BRX1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC140536

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alanine-glyoxylate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-alanine catabolic process, by transamination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in glyoxylate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alanine--glyoxylate aminotransferase 2, mitochondrial
    Names
    (R)-3-amino-2-methylpropionate--pyruvate transaminase
    AGT 2
    D-3-aminoisobutyrate-pyruvate aminotransferase
    D-AIBAT
    D-beta-aminoisobutyrate-pyruvate aminotransferase
    beta-ALAAT II
    beta-alanine-pyruvate aminotransferase
    NP_001069289.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075821.2 → NP_001069289.1  alanine--glyoxylate aminotransferase 2, mitochondrial

      See identical proteins and their annotated locations for NP_001069289.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118402
      UniProtKB/Swiss-Prot
      Q17QF0
      UniProtKB/TrEMBL
      F1MLG7
      Related
      ENSBTAP00000010113.3, ENSBTAT00000010113.4
      Conserved Domains (2) summary
      cd00610
      Location:70 → 505
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
      TIGR00707
      Location:81 → 505
      argD; transaminase, acetylornithine/succinylornithine family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      39119608..39162313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q17QF0.1 GenPept UniProtKB/Swiss-Prot:Q17QF0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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