U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    METTL4 methyltransferase 4, N6-adenosine [ Bos taurus (domestic cattle) ]

    Gene ID: 521222, updated on 4-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    METTL4provided by VGNC
    Official Full Name
    methyltransferase 4, N6-adenosineprovided by VGNC
    Primary source
    VGNC:VGNC:31413
    See related
    BGD:BT18778; Ensembl:ENSBTAG00000021668
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See METTL4 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (36831023..36860537, complement)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343771 Neighboring gene uncharacterized LOC112444165 Neighboring gene NDC80 kinetochore complex component Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables site-specific DNA-methyltransferase (adenine-specific) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA N6-methyladenosine methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    N(6)-adenine-specific methyltransferase METTL4
    Names
    methyltransferase like 4
    NP_001192812.1
    XP_005224233.1
    XP_010817139.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205883.2 → NP_001192812.1  N(6)-adenine-specific methyltransferase METTL4

      See identical proteins and their annotated locations for NP_001192812.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000024
      UniProtKB/TrEMBL
      A0A3Q1MDJ7, A0A3Q1MXE9
      Related
      ENSBTAP00000060382.2, ENSBTAT00000082107.2
      Conserved Domains (1) summary
      cl01947
      Location:278 → 452
      MT-A70; MT-A70

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36831023..36860537 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005224176.5 → XP_005224233.1  N(6)-adenine-specific methyltransferase METTL4 isoform X2

      See identical proteins and their annotated locations for XP_005224233.1

      UniProtKB/TrEMBL
      A0A3Q1MDJ7, A0A3Q1MXE9
      Conserved Domains (1) summary
      cl01947
      Location:278 → 452
      MT-A70; MT-A70

    2. XM_010818837.4 → XP_010817139.1  N(6)-adenine-specific methyltransferase METTL4 isoform X1

      See identical proteins and their annotated locations for XP_010817139.1

      UniProtKB/TrEMBL
      A0A3Q1MDJ7, E1BLJ0
      Related
      ENSBTAP00000028874.3, ENSBTAT00000028874.5
      Conserved Domains (1) summary
      cl01947
      Location:278 → 453
      MT-A70; MT-A70
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials