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    SLC35A3 solute carrier family 35 member A3 [ Bos taurus (domestic cattle) ]

    Gene ID: 520918, updated on 10-Oct-2024

    Summary

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    Official Symbol
    SLC35A3provided by VGNC
    Official Full Name
    solute carrier family 35 member A3provided by VGNC
    Primary source
    VGNC:VGNC:49969
    See related
    BGD:BT10978; Ensembl:ENSBTAG00000012454
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SLC35A3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (43242629..43294364, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase 13 homolog Neighboring gene SAS-6 centriolar assembly protein Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene U5 spliceosomal RNA Neighboring gene uncharacterized LOC112445983 Neighboring gene amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Neighboring gene ferric chelate reductase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation. Thomsen B, et al. Genome Res, 2006 Jan. PMID 16344554, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A defective SLC35A3 gene is associated with severe axial skeletal deformities, symmetric arthrogryposis of the lower limb joints, craniofacial dysmorphism, and cardiac anomalies.
      Title: A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N-acetylglucosamine transporter, causes complex vertebral malformation.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables UDP-galactose transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-N-acetylglucosamine transporter
    Names
    golgi UDP-GlcNAc transporter
    solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
    solute carrier family 35 member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105386.1 → NP_001098856.1  UDP-N-acetylglucosamine transporter

      See identical proteins and their annotated locations for NP_001098856.1

      Status: PROVISIONAL

      Source sequence(s)
      AY160683
      UniProtKB/Swiss-Prot
      A7Z022, Q6YC49
      UniProtKB/TrEMBL
      A0AAA9T694
      Related
      ENSBTAP00000092249.1, ENSBTAT00000111397.1
      Conserved Domains (1) summary
      pfam04142
      Location:1 → 314
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43242629..43294364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005204117.5 → XP_005204174.2  UDP-N-acetylglucosamine transporter isoform X1

      UniProtKB/Swiss-Prot
      A7Z022, Q6YC49

    2. XM_005204120.4 → XP_005204177.1  UDP-N-acetylglucosamine transporter isoform X1

      See identical proteins and their annotated locations for XP_005204177.1

      UniProtKB/Swiss-Prot
      A7Z022, Q6YC49
      UniProtKB/TrEMBL
      A0AAA9T694
      Related
      ENSBTAP00000016519.4, ENSBTAT00000016519.5
      Conserved Domains (1) summary
      pfam04142
      Location:1 → 314
      Nuc_sug_transp; Nucleotide-sugar transporter

    3. XM_024989140.2 → XP_024844908.1  UDP-N-acetylglucosamine transporter isoform X3

      UniProtKB/TrEMBL
      A0AAA9T694
      Related
      ENSBTAP00000090662.1, ENSBTAT00000098480.1
      Conserved Domains (1) summary
      pfam04142
      Location:13 → 326
      Nuc_sug_transp; Nucleotide-sugar transporter

    4. XM_015463747.3 → XP_015319233.1  UDP-N-acetylglucosamine transporter isoform X1

      UniProtKB/Swiss-Prot
      A7Z022, Q6YC49
      UniProtKB/TrEMBL
      A0AAA9T694
      Conserved Domains (1) summary
      pfam04142
      Location:1 → 314
      Nuc_sug_transp; Nucleotide-sugar transporter

    5. XM_005204118.5 → XP_005204175.1  UDP-N-acetylglucosamine transporter isoform X2

      See identical proteins and their annotated locations for XP_005204175.1

      UniProtKB/TrEMBL
      A0AAA9T694
      Conserved Domains (1) summary
      pfam04142
      Location:22 → 335
      Nuc_sug_transp; Nucleotide-sugar transporter
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6YC49.1 GenPept UniProtKB/Swiss-Prot:Q6YC49

    Gene LinkOut

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