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    USP1 ubiquitin specific peptidase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 516328, updated on 4-Oct-2024

    Summary

    Official Symbol
    USP1provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 1provided by VGNC
    Primary source
    VGNC:VGNC:36709
    See related
    BGD:BT12904; Ensembl:ENSBTAG00000020451
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See USP1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (83117498..83129601, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL14-like Neighboring gene dedicator of cytokinesis 7 Neighboring gene angiopoietin like 3 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA cysteine (anticodon ACA)

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Clone Names

    • MGC137005

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in regulation of DNA repair IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 1
    Names
    deubiquitinating enzyme 1
    ubiquitin thioesterase 1
    ubiquitin thiolesterase 1
    ubiquitin-specific-processing protease 1
    NP_001039689.1
    XP_059740389.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046224.1NP_001039689.1  ubiquitin carboxyl-terminal hydrolase 1

      See identical proteins and their annotated locations for NP_001039689.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114087
      UniProtKB/Swiss-Prot
      Q29RP1
      Related
      ENSBTAP00000027254.5, ENSBTAT00000027254.6
      Conserved Domains (1) summary
      cd02671
      Location:58597
      Peptidase_C19O; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      83117498..83129601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059884406.1XP_059740389.1  ubiquitin carboxyl-terminal hydrolase 1 isoform X1

      UniProtKB/TrEMBL
      F1MKU4