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    TGFB1I1 transforming growth factor beta 1 induced transcript 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 515834, updated on 4-Oct-2024

    Summary

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    Official Symbol
    TGFB1I1provided by VGNC
    Official Full Name
    transforming growth factor beta 1 induced transcript 1provided by VGNC
    Primary source
    VGNC:VGNC:35801
    See related
    BGD:BT26439; Ensembl:ENSBTAG00000002391
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TGFB1I1 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (27503152..27509324)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 436-like Neighboring gene armadillo repeat containing 5 Neighboring gene solute carrier family 5 member 2 Neighboring gene RUS family member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC128848

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables muscle alpha-actinin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in muscle structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of filamentous actin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transforming growth factor beta-1-induced transcript 1 protein
    Names
    hic-5
    hydrogen peroxide-inducible clone 5 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035313.1 → NP_001030390.1  transforming growth factor beta-1-induced transcript 1 protein

      See identical proteins and their annotated locations for NP_001030390.1

      Status: PROVISIONAL

      Source sequence(s)
      BC104510
      UniProtKB/TrEMBL
      A0AAF6YJH7
      Conserved Domains (5) summary
      cd09337
      Location:265 → 316
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09409
      Location:324 → 376
      LIM3_Paxillin; The third LIM domain of paxillin
      cd09412
      Location:383 → 434
      LIM4_Leupaxin; The fourth LIM domain of Leupaxin
      cd09336
      Location:206 → 258
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:11 → 178
      Paxillin; Paxillin family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      27503152..27509324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005224909.5 → XP_005224966.1  transforming growth factor beta-1-induced transcript 1 protein isoform X2

      See identical proteins and their annotated locations for XP_005224966.1

      UniProtKB/TrEMBL
      A0AAF6YJH7
      Related
      ENSBTAP00000003094.5, ENSBTAT00000003094.6
      Conserved Domains (5) summary
      cd09337
      Location:265 → 316
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09409
      Location:324 → 376
      LIM3_Paxillin; The third LIM domain of paxillin
      cd09412
      Location:383 → 434
      LIM4_Leupaxin; The fourth LIM domain of Leupaxin
      cd09336
      Location:206 → 258
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:11 → 178
      Paxillin; Paxillin family

    2. XM_005224908.4 → XP_005224965.1  transforming growth factor beta-1-induced transcript 1 protein isoform X1

      See identical proteins and their annotated locations for XP_005224965.1

      UniProtKB/Swiss-Prot
      Q3MHZ4
      UniProtKB/TrEMBL
      A0AAF6YJH7
      Conserved Domains (5) summary
      cd09337
      Location:282 → 333
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09409
      Location:341 → 393
      LIM3_Paxillin; The third LIM domain of paxillin
      cd09412
      Location:400 → 451
      LIM4_Leupaxin; The fourth LIM domain of Leupaxin
      cd09336
      Location:223 → 275
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      pfam03535
      Location:16 → 195
      Paxillin; Paxillin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3MHZ4.2 GenPept UniProtKB/Swiss-Prot:Q3MHZ4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials