U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    IFT88 intraflagellar transport 88 [ Bos taurus (domestic cattle) ]

    Gene ID: 514177, updated on 4-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    IFT88provided by VGNC
    Official Full Name
    intraflagellar transport 88provided by VGNC
    Primary source
    VGNC:VGNC:30074
    See related
    BGD:BT22776; Ensembl:ENSBTAG00000014286
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See IFT88 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (35853118..35914399, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene EEF1A lysine methyltransferase 1 Neighboring gene uncharacterized LOC132346770 Neighboring gene interleukin 17D Neighboring gene crystallin lambda 1 Neighboring gene snRNA-activating protein complex subunit 1-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. Baker SA, et al. J Biol Chem, 2003 Sep 5. PMID 12821668
    2. RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. Khanna H, et al. J Biol Chem, 2005 Sep 30. PMID 16043481, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinesin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in inner ear receptor cell stereocilium organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intraciliary transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in kidney development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in non-motile cilium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ciliary base IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in non-motile cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    intraflagellar transport protein 88 homolog
    Names
    intraflagellar transport 88 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110786.3 → NP_001104256.2  intraflagellar transport protein 88 homolog

      Status: INFERRED

      Source sequence(s)
      NKLS02000012
      UniProtKB/TrEMBL
      E1BLX1
      Conserved Domains (2) summary
      sd00006
      Location:485 → 513
      TPR; TPR repeat [structural motif]
      cl26002
      Location:213 → 692
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35853118..35914399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213777.5 → XP_005213834.1  intraflagellar transport protein 88 homolog isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MMQ6
      Related
      ENSBTAP00000073104.2, ENSBTAT00000067455.2
      Conserved Domains (7) summary
      COG0457
      Location:392 → 650
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:448 → 476
      TPR; TPR repeat [structural motif]
      cd15832
      Location:478 → 511
      SNAP; TPR repeat [structural motif]
      pfam00515
      Location:201 → 228
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:162 → 223
      TPR_11; TPR repeat
      pfam13424
      Location:194 → 267
      TPR_12; Tetratricopeptide repeat
      cl24038
      Location:464 → 686
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family

    2. XM_005213776.5 → XP_005213833.1  intraflagellar transport protein 88 homolog isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MNB3
      Related
      ENSBTAP00000073403.2, ENSBTAT00000078675.2
      Conserved Domains (5) summary
      COG0457
      Location:410 → 668
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:466 → 494
      TPR; TPR repeat [structural motif]
      cd15832
      Location:496 → 529
      SNAP; TPR repeat [structural motif]
      pfam00515
      Location:219 → 246
      TPR_1; Tetratricopeptide repeat
      cl24038
      Location:482 → 704
      SNAP; Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family

    3. XM_005213778.5 → XP_005213835.1  intraflagellar transport protein 88 homolog isoform X1

      See identical proteins and their annotated locations for XP_005213835.1

      UniProtKB/TrEMBL
      E1BLX1
      Conserved Domains (2) summary
      sd00006
      Location:485 → 513
      TPR; TPR repeat [structural motif]
      cl26002
      Location:213 → 692
      TPR_11; TPR repeat

    4. XM_059892031.1 → XP_059748014.1  intraflagellar transport protein 88 homolog isoform X1

      UniProtKB/TrEMBL
      E1BLX1

    5. XM_005213775.5 → XP_005213832.1  intraflagellar transport protein 88 homolog isoform X1

      See identical proteins and their annotated locations for XP_005213832.1

      UniProtKB/TrEMBL
      E1BLX1
      Related
      ENSBTAP00000018980.5, ENSBTAT00000018980.7
      Conserved Domains (2) summary
      sd00006
      Location:485 → 513
      TPR; TPR repeat [structural motif]
      cl26002
      Location:213 → 692
      TPR_11; TPR repeat
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials