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    DGKD diacylglycerol kinase delta [ Bos taurus (domestic cattle) ]

    Gene ID: 513389, updated on 10-Oct-2024

    Summary

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    Official Symbol
    DGKDprovided by VGNC
    Official Full Name
    diacylglycerol kinase deltaprovided by VGNC
    Primary source
    VGNC:VGNC:28026
    See related
    BGD:BT28971; Ensembl:ENSBTAG00000020616
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See DGKD in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (113062330..113172643)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene autophagy related 16 like 1 Neighboring gene small Cajal body-specific RNA 6 Neighboring gene S-antigen visual arrestin Neighboring gene ubiquitin specific peptidase 40 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene UDP-glucuronosyltransferase 1A3-like Neighboring gene UDP glucuronosyltransferase 1 family, polypeptide A6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC128923

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein homodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in diacylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diacylglycerol kinase delta
    Names
    diacylglycerol kinase, delta 130kDa
    NP_001030359.2
    XP_024843894.1
    XP_059739736.1
    XP_059739738.1
    XP_059739744.1
    XP_059739746.1
    XP_059739750.1
    XP_059739753.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035282.2 → NP_001030359.2  diacylglycerol kinase delta

      See identical proteins and their annotated locations for NP_001030359.2

      Status: PROVISIONAL

      Source sequence(s)
      BC149377
      UniProtKB/TrEMBL
      A0A3Q1NJA6, A6QPL5, F1MDC8
      Related
      ENSBTAP00000095033.1, ENSBTAT00000126743.1
      Conserved Domains (8) summary
      cd09575
      Location:1142 → 1206
      SAM_DGK-delta; SAM domain of diacylglycerol kinase delta
      smart00109
      Location:236 → 286
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00454
      Location:1143 → 1206
      SAM; Sterile alpha motif
      smart00045
      Location:764 → 921
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:323 → 445
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:164 → 213
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:55 → 151
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
      pfam00169
      Location:54 → 142
      PH; PH domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      113062330..113172643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883753.1 → XP_059739736.1  diacylglycerol kinase delta isoform X1

    2. XM_059883761.1 → XP_059739744.1  diacylglycerol kinase delta isoform X4

      Related
      ENSBTAP00000064854.2, ENSBTAT00000068942.2

    3. XM_024988126.1 → XP_024843894.1  diacylglycerol kinase delta isoform X3

      UniProtKB/TrEMBL
      A0A3Q1NJA6, A0AAF6DLM4
      Related
      ENSBTAP00000027473.7, ENSBTAT00000027473.7
      Conserved Domains (6) summary
      cd09575
      Location:1143 → 1207
      SAM_DGK-delta; SAM domain of diacylglycerol kinase delta
      smart00109
      Location:236 → 286
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:765 → 922
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:323 → 445
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00029
      Location:164 → 213
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd13274
      Location:55 → 151
      PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

    4. XM_059883755.1 → XP_059739738.1  diacylglycerol kinase delta isoform X2

    5. XM_059883763.1 → XP_059739746.1  diacylglycerol kinase delta isoform X5

    6. XM_059883770.1 → XP_059739753.1  diacylglycerol kinase delta isoform X5

    7. XM_059883767.1 → XP_059739750.1  diacylglycerol kinase delta isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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