RARRES2 retinoic acid receptor responder 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: RARRES2provided by VGNC
Official Full Name: retinoic acid receptor responder 2provided by VGNC
Primary source: VGNC:VGNC:33732
See related: BGD:BT24997
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: TIG2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (112667461..112753044, complement)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that the fat and energy moblization during lactation influences circulating retinoic acid receptor responder protein 2 (RARRES2) levels as well as the expression of RARRES2 and chemokine-like receptor 1 (CMKLR1) in subcutaneous adipose tissue (SAT) and ovarian cells.
Title: Possible involvement of the RARRES2/CMKLR1-system in metabolic and reproductive parameters in Holstein dairy cows.
These results suggest that Chemerin promotes lipolysis in mature adipocytes and induces adipogenesis during preadipocyte re-differentiation, further indicating a dual role for Chemerin in the deposition of intramuscular fat in ruminant animals.
Title: The adipokine Chemerin induces lipolysis and adipogenesis in bovine intramuscular adipocytes.
chemerin is a novel regulator of lactogenesis via its own receptor in bovine mammary epithelial cells
Title: Chemerin is a novel regulator of lactogenesis in bovine mammary epithelial cells.

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General gene information

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Markers

MARC_77240-77241:1241473956:29 (e-PCR)
- UniSTS:528123

MARC_77244-77245:1244121418:1 (e-PCR)
- UniSTS:528124

MARC_77246-77247:1241729091:7 (e-PCR)
- UniSTS:528125

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of lipid catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: retinoic acid receptor responder protein 2

Names: chemerin; retinoic acid receptor responder (tazarotene induced) 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.