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    PRODH2 proline dehydrogenase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 508542, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PRODH2provided by VGNC
    Official Full Name
    proline dehydrogenase 2provided by VGNC
    Primary source
    VGNC:VGNC:33360
    See related
    BGD:BT12816; Ensembl:ENSBTAG00000031772
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    HYPDH
    Orthologs
    human mouse all
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    Genomic context

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    See PRODH2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (46508441..46524659, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 33 Neighboring gene inactive serine/threonine-protein kinase TEX14-like Neighboring gene U6 spliceosomal RNA Neighboring gene NPHS1 adhesion molecule, nephrin Neighboring gene kirre like nephrin family adhesion molecule 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables proline dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proline catabolic process to glutamate IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxyproline dehydrogenase
    Names
    probable proline dehydrogenase 2
    probable proline oxidase 2
    proline dehydrogenase (oxidase) 2
    NP_001098437.1
    XP_059732564.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104967.2 → NP_001098437.1  hydroxyproline dehydrogenase

      See identical proteins and their annotated locations for NP_001098437.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149682
      UniProtKB/Swiss-Prot
      A6QQ74
      UniProtKB/TrEMBL
      F1MZH9
      Related
      ENSBTAP00000042469.4, ENSBTAT00000045048.4
      Conserved Domains (2) summary
      PLN02681
      Location:28 → 446
      PLN02681; proline dehydrogenase
      pfam01619
      Location:212 → 439
      Pro_dh; Proline dehydrogenase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46508441..46524659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876581.1 → XP_059732564.1  hydroxyproline dehydrogenase isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6QQ74.1 GenPept UniProtKB/Swiss-Prot:A6QQ74

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials