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    ESRRA estrogen related receptor alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 507834, updated on 4-Oct-2024

    Summary

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    Official Symbol
    ESRRAprovided by VGNC
    Official Full Name
    estrogen related receptor alphaprovided by VGNC
    Primary source
    VGNC:VGNC:28608
    See related
    Ensembl:ENSBTAG00000008645
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ESRRA in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (42603633..42611807)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 4 Neighboring gene catsper channel auxiliary subunit zeta Neighboring gene tRNA methyltransferase activator subunit 11-2 Neighboring gene peroxiredoxin 5 Neighboring gene coiled-coil domain containing 88B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptional regulators transforming growth factor-β1 and estrogen-related receptor-α identified as putative mediators of calf rumen epithelial tissue development and function during weaning. Connor EE, et al. J Dairy Sci, 2014 Jul. PMID 24767884
    2. Estrogen receptor beta (ERbeta) is expressed differently from ERalpha in bovine placentomes. Schuler G, et al. Exp Clin Endocrinol Diabetes, 2005 Feb. PMID 15772903
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results identify TGFB1 and ESRRA as likely transcriptional regulators of rumen epithelial development and energy metabolism, respectively, and provide targets for modulation of rumen development and function in the growing calf.
      Title: Transcriptional regulators transforming growth factor-β1 and estrogen-related receptor-α identified as putative mediators of calf rumen epithelial tissue development and function during weaning.
    2. ERalpha, is only expressed in the caruncle of the placenta.
      Title: Estrogen receptor beta (ERbeta) is expressed differently from ERalpha in bovine placentomes.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear steroid receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    steroid hormone receptor ERR1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191373.2 → NP_001178302.1  steroid hormone receptor ERR1

      See identical proteins and their annotated locations for NP_001178302.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000029
      UniProtKB/TrEMBL
      F1MBX3
      Conserved Domains (2) summary
      cd06946
      Location:196 → 419
      NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors
      cd07170
      Location:73 → 168
      NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42603633..42611807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010821061.4 → XP_010819363.1  steroid hormone receptor ERR1 isoform X1

      See identical proteins and their annotated locations for XP_010819363.1

      UniProtKB/TrEMBL
      F1MBX3
      Related
      ENSBTAP00000036275.4, ENSBTAT00000036417.6
      Conserved Domains (2) summary
      cd06946
      Location:196 → 419
      NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors
      cd07170
      Location:73 → 168
      NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers

    2. XM_010821062.4 → XP_010819364.1  steroid hormone receptor ERR1 isoform X1

      See identical proteins and their annotated locations for XP_010819364.1

      UniProtKB/TrEMBL
      F1MBX3
      Conserved Domains (2) summary
      cd06946
      Location:196 → 419
      NR_LBD_ERR; The ligand binding domain of estrogen receptor-related nuclear receptors
      cd07170
      Location:73 → 168
      NR_DBD_ERR; DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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