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    PRPF8 pre-mRNA processing factor 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 507371, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PRPF8provided by VGNC
    Official Full Name
    pre-mRNA processing factor 8provided by VGNC
    Primary source
    VGNC:VGNC:33383
    See related
    Ensembl:ENSBTAG00000011488
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PRPF8 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (22753896..22786522, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene scavenger receptor class F member 1 Neighboring gene Rab interacting lysosomal protein Neighboring gene ribosomal protein L15a pseudogene Neighboring gene TLC domain containing 2 Neighboring gene microRNA mir-3600 Neighboring gene microRNA mir-22 Neighboring gene WD repeat domain 81

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC159991

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables U1 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U2 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U5 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U6 snRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pre-mRNA intronic binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spliceosomal tri-snRNP complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U5 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA-processing-splicing factor 8
    Names
    PRP8 pre-mRNA processing factor 8 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105638.1 → NP_001099108.1  pre-mRNA-processing-splicing factor 8

      See identical proteins and their annotated locations for NP_001099108.1

      Status: PROVISIONAL

      Source sequence(s)
      BC153223
      UniProtKB/TrEMBL
      A0AAA9SPZ8, A7Z025
      Related
      ENSBTAP00000043577.2, ENSBTAT00000046260.3
      Conserved Domains (1) summary
      COG5178
      Location:1 → 2335
      PRP8; U5 snRNP spliceosome subunit [RNA processing and modification]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      22753896..22786522 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220080.4 → XP_005220137.1  pre-mRNA-processing-splicing factor 8 isoform X1

      See identical proteins and their annotated locations for XP_005220137.1

      UniProtKB/TrEMBL
      A0AAA9SPZ8, A7Z025
      Conserved Domains (1) summary
      COG5178
      Location:1 → 2335
      PRP8; U5 snRNP spliceosome subunit [RNA processing and modification]

    2. XM_024979809.2 → XP_024835577.1  pre-mRNA-processing-splicing factor 8 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SPZ8, A7Z025
      Conserved Domains (1) summary
      COG5178
      Location:1 → 2335
      PRP8; U5 snRNP spliceosome subunit [RNA processing and modification]
    Nucleotide Protein Strain
    Heading Accession and Version

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