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    GIGYF2 GRB10 interacting GYF protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 506913, updated on 10-Oct-2024

    Summary

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    Official Symbol
    GIGYF2provided by VGNC
    Official Full Name
    GRB10 interacting GYF protein 2provided by VGNC
    Primary source
    VGNC:VGNC:29356
    See related
    BGD:BT10158; Ensembl:ENSBTAG00000014079
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TNRC15
    Orthologs
    human mouse all
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    Genomic context

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    See GIGYF2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (112454953..112584312)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104971852 Neighboring gene EF-hand domain family member D1 Neighboring gene potassium inwardly rectifying channel subfamily J member 13 Neighboring gene secondary ossification center associated regulator of chondrocyte maturation Neighboring gene neuronal guanine nucleotide exchange factor Neighboring gene neuraminidase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159971

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin-like growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in proximal dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GRB10-interacting GYF protein 2
    Names
    trinucleotide repeat containing 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101877.1 → NP_001095347.1  GRB10-interacting GYF protein 2

      See identical proteins and their annotated locations for NP_001095347.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151282
      UniProtKB/TrEMBL
      A0AAA9TUB6, A7MB14
      Related
      ENSBTAP00000018720.6, ENSBTAT00000018720.6
      Conserved Domains (1) summary
      cd00072
      Location:532 → 587
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      112454953..112584312
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024986645.2 → XP_024842413.1  GRB10-interacting GYF protein 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TUB6, F6QXG7
      Conserved Domains (1) summary
      cd00072
      Location:532 → 587
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    2. XM_059882815.1 → XP_059738798.1  GRB10-interacting GYF protein 2 isoform X2

    3. XM_024986654.2 → XP_024842422.1  GRB10-interacting GYF protein 2 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TUB6
      Conserved Domains (1) summary
      cd00072
      Location:526 → 581
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    4. XM_024986639.2 → XP_024842407.1  GRB10-interacting GYF protein 2 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TUB6, F6QXG7
      Conserved Domains (1) summary
      cd00072
      Location:532 → 587
      GYF; GYF domain: contains conserved Gly-Tyr-Phe residues; Proline-binding domain in CD2-binding and other proteins. Involved in signaling lymphocyte activity. Also present in other unrelated proteins (mainly unknown) derived from diverse eukaryotic species.

    5. XM_059882823.1 → XP_059738806.1  GRB10-interacting GYF protein 2 isoform X5

      UniProtKB/TrEMBL
      A0AAA9ST07
      Related
      ENSBTAP00000089546.1, ENSBTAT00000113039.1

    6. XM_059882821.1 → XP_059738804.1  GRB10-interacting GYF protein 2 isoform X4

      Related
      ENSBTAP00000084378.1, ENSBTAT00000118691.1

    7. XM_059882826.1 → XP_059738809.1  GRB10-interacting GYF protein 2 isoform X6

    8. XM_059882831.1 → XP_059738814.1  GRB10-interacting GYF protein 2 isoform X7

    Nucleotide Protein Strain
    Heading Accession and Version

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