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    PDXP pyridoxal phosphatase [ Bos taurus (domestic cattle) ]

    Gene ID: 506308, updated on 4-Oct-2024

    Summary

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    Official Symbol
    PDXPprovided by VGNC
    Official Full Name
    pyridoxal phosphataseprovided by VGNC
    Primary source
    VGNC:VGNC:32722
    See related
    BGD:BT20768; Ensembl:ENSBTAG00000030255
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PDXP in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (109498768..109504538)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 1 Neighboring gene SH3 domain binding protein 1 Neighboring gene uncharacterized LOC100847870 Neighboring gene galectin 1 Neighboring gene nucleolar protein 12 Neighboring gene microRNA mir-2438

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. Gohla A, et al. Nat Cell Biol, 2005 Jan. PMID 15580268
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC126941

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chronophin
    Names
    PLP phosphatase
    protein serine phosphatase
    pyridoxal (pyridoxine, vitamin B6) phosphatase
    pyridoxal phosphate phosphatase
    NP_001030207.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035035.2 → NP_001030207.1  chronophin

      See identical proteins and their annotated locations for NP_001030207.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103329
      UniProtKB/Swiss-Prot
      Q3ZBF9
      UniProtKB/TrEMBL
      F1MW60
      Related
      ENSBTAP00000016505.3, ENSBTAT00000016505.5
      Conserved Domains (3) summary
      TIGR01452
      Location:18 → 290
      PGP_euk; phosphoglycolate/pyridoxal phosphate phosphatase family
      pfam13242
      Location:210 → 290
      Hydrolase_like; HAD-hyrolase-like
      pfam13344
      Location:22 → 128
      Hydrolase_6; Haloacid dehalogenase-like hydrolase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      109498768..109504538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZBF9.1 GenPept UniProtKB/Swiss-Prot:Q3ZBF9

    Gene LinkOut

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    Research Materials