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    MFF mitochondrial fission factor [ Bos taurus (domestic cattle) ]

    Gene ID: 506291, updated on 10-Oct-2024

    Summary

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    Gene symbol
    MFF
    Gene description
    mitochondrial fission factor
    See related
    Ensembl:ENSBTAG00000021319
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    C2orf33; C2H2orf33
    Orthologs
    human mouse all
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    Genomic context

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    See MFF in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (115486670..115515501)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene rhomboid domain containing 1 Neighboring gene collagen type IV alpha 4 chain Neighboring gene collagen type IV alpha 3 chain Neighboring gene transmembrane 4 L six family member 20 Neighboring gene ArfGAP with FG repeats 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. Gandre-Babbe S, et al. Mol Biol Cell, 2008 Jun. PMID 18353969, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC127725

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of mitochondrial fission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial fission factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034267.3 → NP_001029439.1  mitochondrial fission factor isoform 10

      See identical proteins and their annotated locations for NP_001029439.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/Swiss-Prot
      Q3ZCD8
      UniProtKB/TrEMBL
      A0AAA9T2H1
      Conserved Domains (1) summary
      pfam05644
      Location:1 → 218
      Miff; Mitochondrial and peroxisomal fission factor Mff

    2. NM_001428903.1 → NP_001415832.1  mitochondrial fission factor isoform 1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002

    3. NM_001428904.1 → NP_001415833.1  mitochondrial fission factor isoform 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002

    4. NM_001428905.1 → NP_001415834.1  mitochondrial fission factor isoform 3

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002

    5. NM_001428906.1 → NP_001415835.1  mitochondrial fission factor isoform 4

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A0A3Q1MNP7

    6. NM_001428907.1 → NP_001415836.1  mitochondrial fission factor isoform 5

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A0A3Q1MNF4

    7. NM_001428908.1 → NP_001415837.1  mitochondrial fission factor isoform 6

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002

    8. NM_001428909.1 → NP_001415838.1  mitochondrial fission factor isoform 7

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002

    9. NM_001428910.1 → NP_001415839.1  mitochondrial fission factor isoform 8

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A5PK60

    10. NM_001428911.1 → NP_001415840.1  mitochondrial fission factor isoform 9

      Status: VALIDATED

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A0AAF6Z9G5

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      115486670..115515501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202901.4 → XP_005202958.1  mitochondrial fission factor isoform X1

      Conserved Domains (1) summary
      pfam05644
      Location:27 → 379
      Miff; Mitochondrial and peroxisomal fission factor Mff

    2. XM_005202902.4 → XP_005202959.1  mitochondrial fission factor isoform X2

      Conserved Domains (1) summary
      pfam05644
      Location:27 → 368
      Miff; Mitochondrial and peroxisomal fission factor Mff

    3. XM_005202903.4 → XP_005202960.1  mitochondrial fission factor isoform X4

      See identical proteins and their annotated locations for XP_005202960.1

      UniProtKB/TrEMBL
      E1BLP4
      Related
      ENSBTAP00000028421.4, ENSBTAT00000028421.5
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 353
      Miff; Mitochondrial and peroxisomal fission factor Mff

    4. XM_005202905.4 → XP_005202962.1  mitochondrial fission factor isoform X5

      UniProtKB/TrEMBL
      E1BLP4
      Related
      ENSBTAP00000071201.2, ENSBTAT00000070018.2
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 342
      Miff; Mitochondrial and peroxisomal fission factor Mff

    5. XM_024999781.2 → XP_024855549.1  mitochondrial fission factor isoform X9

      UniProtKB/TrEMBL
      A0AAA9T2H1
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 300
      Miff; Mitochondrial and peroxisomal fission factor Mff

    6. XM_005202906.4 → XP_005202963.1  mitochondrial fission factor isoform X6

      Related
      ENSBTAP00000071057.1, ENSBTAT00000080985.2
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 328
      Miff; Mitochondrial and peroxisomal fission factor Mff

    7. XM_005202907.4 → XP_005202964.1  mitochondrial fission factor isoform X7

      Related
      ENSBTAP00000060579.2, ENSBTAT00000081386.2
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 317
      Miff; Mitochondrial and peroxisomal fission factor Mff

    8. XM_005202912.4 → XP_005202969.1  mitochondrial fission factor isoform X10

      Related
      ENSBTAP00000050661.1, ENSBTAT00000054977.3
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 264
      Miff; Mitochondrial and peroxisomal fission factor Mff

    9. XM_005202913.4 → XP_005202970.1  mitochondrial fission factor isoform X11

      Related
      ENSBTAP00000028425.6, ENSBTAT00000028425.7
      Conserved Domains (1) summary
      pfam05644
      Location:27 → 244
      Miff; Mitochondrial and peroxisomal fission factor Mff

    10. XM_005202904.4 → XP_005202961.1  mitochondrial fission factor isoform X3

      Conserved Domains (1) summary
      pfam05644
      Location:1 → 353
      Miff; Mitochondrial and peroxisomal fission factor Mff

    11. XM_005202909.4 → XP_005202966.1  mitochondrial fission factor isoform X8

      Conserved Domains (1) summary
      pfam05644
      Location:1 → 302
      Miff; Mitochondrial and peroxisomal fission factor Mff
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZCD8.1 GenPept UniProtKB/Swiss-Prot:Q3ZCD8

    Gene LinkOut

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