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    eef1akmt2 EEF1A lysine methyltransferase 2 [ Danio rerio (zebrafish) ]

    Gene ID: 503749, updated on 18-Sep-2024

    Summary

    Official Symbol
    eef1akmt2provided by ZNC
    Official Full Name
    EEF1A lysine methyltransferase 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050306-30
    See related
    Ensembl:ENSDARG00000102144 AllianceGenome:ZFIN:ZDB-GENE-050306-30
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mettl10; zgc:110805
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Predicted to act upstream of or within methylation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human EEF1AKMT2 (EEF1A lysine methyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    See eef1akmt2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (31820541..31823666)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108179780 Neighboring gene Rho GTPase activating protein 5 Neighboring gene abraxas 2, BRISC complex subunit Neighboring gene inhibitory synaptic factor 2Ab Neighboring gene uncharacterized LOC103909048 Neighboring gene ADAM metallopeptidase domain 12b

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_007128.7 Chromosome 17 Reference GRCz11 Primary Assembly

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-lysine N-methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-lysine methylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    EEF1A lysine methyltransferase 2
    Names
    methyltransferase like 10
    methyltransferase-like protein 10
    protein-lysine N-methyltransferase mettl10
    NP_001013345.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013327.1NP_001013345.1  EEF1A lysine methyltransferase 2

      See identical proteins and their annotated locations for NP_001013345.1

      Status: PROVISIONAL

      Source sequence(s)
      BC090299
      UniProtKB/Swiss-Prot
      Q5D013
      Related
      ENSDARP00000148805.1, ENSDART00000192607.1
      Conserved Domains (2) summary
      COG0500
      Location:38190
      SmtA; SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
      pfam12847
      Location:75188
      Methyltransf_18; Methyltransferase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      31820541..31823666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)