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    P2RY12 purinergic receptor P2Y12 [ Sus scrofa (pig) ]

    Gene ID: 503659, updated on 17-Aug-2024

    Summary

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    Official Symbol
    P2RY12provided by VGNC
    Official Full Name
    purinergic receptor P2Y12provided by VGNC
    Primary source
    VGNC:VGNC:91124
    See related
    Ensembl:ENSSSCG00000011713
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    P2Y12R
    Expression
    Ubiquitous expression in lung (RPKM 1.8), spleen (RPKM 1.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See P2RY12 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (91522754..91572195, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (99604550..99654172, complement)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 12L Neighboring gene G protein-coupled receptor 87 Neighboring gene purinergic receptor P2Y13 Neighboring gene immunoglobulin superfamily member 10 Neighboring gene uncharacterized LOC110256258

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled purinergic nucleotide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in blood coagulation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    P2Y purinoceptor 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173518.1 → NP_001166989.1  P2Y purinoceptor 12

      See identical proteins and their annotated locations for NP_001166989.1

      Status: PROVISIONAL

      Source sequence(s)
      GU386351
      UniProtKB/TrEMBL
      A0A4X1SWV1, D3Y271
      Conserved Domains (2) summary
      pfam00001
      Location:58 → 294
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34 → 209
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      91522754..91572195 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021068626.1 → XP_020924285.1  P2Y purinoceptor 12 isoform X1

      UniProtKB/TrEMBL
      A0A286ZL52, A0A8D0PQ42, A0A8D1DD10, A0A8D1VX06
      Related
      ENSSSCP00000061605.1, ENSSSCT00000073148.2
      Conserved Domains (1) summary
      cd15150
      Location:23 → 305
      7tmA_P2Y12; P2Y purinoceptor 12, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. XM_005669926.3 → XP_005669983.1  P2Y purinoceptor 12 isoform X1

      See identical proteins and their annotated locations for XP_005669983.1

      UniProtKB/TrEMBL
      A0A286ZL52, A0A8D0PQ42, A0A8D1DD10, A0A8D1VX06
      Conserved Domains (1) summary
      cd15150
      Location:23 → 305
      7tmA_P2Y12; P2Y purinoceptor 12, member of the class A family of seven-transmembrane G protein-coupled receptors

    3. XM_021068624.1 → XP_020924283.1  P2Y purinoceptor 12 isoform X1

      UniProtKB/TrEMBL
      A0A286ZL52, A0A8D0PQ42, A0A8D1DD10, A0A8D1VX06
      Related
      ENSSSCP00000032294.1, ENSSSCT00000054315.3
      Conserved Domains (1) summary
      cd15150
      Location:23 → 305
      7tmA_P2Y12; P2Y purinoceptor 12, member of the class A family of seven-transmembrane G protein-coupled receptors

    4. XM_021068625.1 → XP_020924284.1  P2Y purinoceptor 12 isoform X1

      UniProtKB/TrEMBL
      A0A286ZL52, A0A8D0PQ42, A0A8D1DD10, A0A8D1VX06
      Conserved Domains (1) summary
      cd15150
      Location:23 → 305
      7tmA_P2Y12; P2Y purinoceptor 12, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version

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