ABHD5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase [Sus scrofa (pig)] - Gene

Summary

Official Symbol: ABHD5provided by VGNC
Official Full Name: abhydrolase domain containing 5, lysophosphatidic acid acyltransferaseprovided by VGNC
Primary source: VGNC:VGNC:97860
See related: Ensembl:ENSSSCG00000011297
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: CGI-58
Expression: Broad expression in liver (RPKM 74.6), subcutaneous adipose (RPKM 61.1) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	13	NC_010455.5 (27006331..27053760)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	13	NC_010455.4 (29834219..29881698)

Chromosome 13 - NC_010455.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.
Title: Alternative splicing and developmental and hormonal regulation of porcine comparative gene identification-58 (CGI-58) mRNA.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in negative regulation of sequestering of triglyceride	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of triglyceride catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in lipid droplet	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5

Names: abhydrolase domain-containing protein 5; alpha/beta hydrolase domain-containing 5; lipid droplet binding protein

NP_001012407.1

EC 2.3.1.51

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012407.1 → NP_001012407.1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5

See identical proteins and their annotated locations for NP_001012407.1

Status: PROVISIONAL

Source sequence(s)

AY902463

UniProtKB/Swiss-Prot

Q5EE05

UniProtKB/TrEMBL

A0A8D0MRY0, K4PIH7

Related

ENSSSCP00000012044.4, ENSSSCT00000012367.4

Conserved Domains (2) summary

PLN02894
Location:1 → 345

PLN02894; hydrolase, alpha/beta fold family protein

pfam12695
Location:103 → 194

Abhydrolase_5; Alpha/beta hydrolase family