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    FCN1 ficolin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 497016, updated on 10-Oct-2024

    Summary

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    Gene symbol
    FCN1
    Gene description
    ficolin 1
    See related
    Ensembl:ENSBTAG00000048155
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    FCN2; FCNB
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    Genomic context

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    See FCN1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (105441477..105450292, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein SPEM3-like Neighboring gene collagen type V alpha 1 chain Neighboring gene olfactomedin 1 Neighboring gene uncharacterized LOC132346652

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ficolin-2
    Names
    L-ficolin
    collagen/fibrinogen domain-containing protein 2
    ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
    ficolin (collagen/fibrinogen domain containing) 1
    ficolin B
    ficolin-beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010996.1 → NP_001010996.1  ficolin-2 precursor

      See identical proteins and their annotated locations for NP_001010996.1

      Status: PROVISIONAL

      Source sequence(s)
      AY860499
      UniProtKB/Swiss-Prot
      Q5I2E5
      UniProtKB/TrEMBL
      A0A3Q1M1V7
      Related
      ENSBTAP00000067349.1, ENSBTAT00000066723.2
      Conserved Domains (2) summary
      pfam01391
      Location:55 → 109
      Collagen; Collagen triple helix repeat (20 copies)
      cd00087
      Location:118 → 327
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      105441477..105450292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891058.1 → XP_059747041.1  ficolin-2 isoform X1

    2. XM_005213509.5 → XP_005213566.1  ficolin-2 isoform X2

      See identical proteins and their annotated locations for XP_005213566.1

      UniProtKB/TrEMBL
      A4FV99
      Related
      ENSBTAP00000055640.1, ENSBTAT00000065623.2
      Conserved Domains (2) summary
      pfam01391
      Location:51 → 105
      Collagen; Collagen triple helix repeat (20 copies)
      cd00087
      Location:189 → 398
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5I2E5.1 GenPept UniProtKB/Swiss-Prot:Q5I2E5

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