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    Ly49s6 Ly49 stimulatory receptor 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 494196, updated on 18-Sep-2024

    Summary

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    Symbol
    Ly49s6provided by RGD
    Full Name
    Ly49 stimulatory receptor 6provided by RGD
    Primary source
    RGD:1549735
    See related
    EnsemblRapid:ENSRNOG00000053337 AllianceGenome:RGD:1549735
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 61.5), Lung (RPKM 22.8) and 4 other tissues See more
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    Genomic context

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    See Ly49s6 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (165765947..165790123, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (164080442..164104904, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (164428761..164453267, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene Ly49 inhibitory receptor 5 Neighboring gene killer cell lectin-like receptor subfamily A, member 22 Neighboring gene Ly49 stimulatory receptor 4 Neighboring gene Ly49 inhibitory receptor 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex. Nylenna O, et al. Eur J Immunol, 2005 Jan. PMID 15593300
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ly49 stimulatory receptor 6; ly49 stimulatory receptor 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001389229.1 → NP_001376158.1  Ly49 stimulatory receptor 6

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2K9W0, A0A1B2LPZ6
      Related
      ENSRNOP00000075151.1, ENSRNOT00000083610.3
      Conserved Domains (2) summary
      cd03593
      Location:69 → 182
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:38 → 82
      Ly49; Ly49-like protein, N-terminal region

    RNA

    1. NR_171199.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      165765947..165790123 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592745.3 → XP_017448234.1  ly49 stimulatory receptor 6 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9W0, A0A1B2LPZ6
      Conserved Domains (2) summary
      cd03593
      Location:69 → 182
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:38 → 82
      Ly49; Ly49-like protein, N-terminal region

    2. XM_017592748.3 → XP_017448237.1  ly49 stimulatory receptor 6 isoform X2

      UniProtKB/TrEMBL
      A0A0G2JZN5, A0A0G2K4W0, Q5M837
      Related
      ENSRNOP00000072255.1, ENSRNOT00000079975.3
      Conserved Domains (1) summary
      pfam08391
      Location:38 → 137
      Ly49; Ly49-like protein, N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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