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    MSN moesin [ Canis lupus familiaris (dog) ]

    Gene ID: 491924, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MSNprovided by VGNC
    Official Full Name
    moesinprovided by VGNC
    Primary source
    VGNC:VGNC:43447
    See related
    Ensembl:ENSCAFG00845027053
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See MSN in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (51673014..51739539)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (41546746..41613249)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (50900835..50967356)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (49637614..49704123)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (50985533..51052067)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene natural cytotoxicity triggering receptor 3 ligand 1-like Neighboring gene ribosomal protein, large, P1 pseudogene Neighboring gene uncharacterized LOC119868451 Neighboring gene V-set and immunoglobulin domain containing 4 Neighboring gene microRNA mir-223 Neighboring gene signal peptidase complex subunit 1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ezrin and moesin expression in canine and feline osteosarcoma. Hlavaty J, et al. Histol Histopathol, 2017 Aug. PMID 27900754

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. analysis of ezrin and moesin expression in canine and feline osteosarcoma
      Title: Ezrin and moesin expression in canine and feline osteosarcoma.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of early endosome to late endosome transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein localization to early endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of organelle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in apical part of cell IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in filopodium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microvillus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    moesin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      51673014..51739539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038450167.1 → XP_038306095.1  moesin isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:1 → 195
      B41; Band 4.1 homologues
      cd13194
      Location:189 → 285
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:336 → 566
      ERM; Ezrin/radixin/moesin family

    2. XM_038450166.1 → XP_038306094.1  moesin isoform X2

      UniProtKB/TrEMBL
      A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13194
      Location:200 → 296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:347 → 577
      ERM; Ezrin/radixin/moesin family

    3. XM_038450165.1 → XP_038306093.1  moesin isoform X1

      UniProtKB/TrEMBL
      A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
      Related
      ENSCAFP00845037623.1, ENSCAFT00845047957.1
      Conserved Domains (3) summary
      smart00295
      Location:22 → 221
      B41; Band 4.1 homologues
      cd13194
      Location:215 → 311
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:362 → 592
      ERM; Ezrin/radixin/moesin family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      49637614..49704123
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038523611.1 → XP_038379539.1  moesin isoform X3

      Conserved Domains (3) summary
      smart00295
      Location:1 → 195
      B41; Band 4.1 homologues
      cd13194
      Location:189 → 285
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:336 → 566
      ERM; Ezrin/radixin/moesin family

    2. XM_038523610.1 → XP_038379538.1  moesin isoform X2

      Conserved Domains (3) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13194
      Location:200 → 296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:347 → 577
      ERM; Ezrin/radixin/moesin family

    3. XM_038523609.1 → XP_038379537.1  moesin isoform X1

      Conserved Domains (3) summary
      smart00295
      Location:22 → 221
      B41; Band 4.1 homologues
      cd13194
      Location:215 → 311
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:362 → 592
      ERM; Ezrin/radixin/moesin family

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      50985533..51052067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038652107.1 → XP_038508035.1  moesin isoform X3

      Conserved Domains (3) summary
      smart00295
      Location:1 → 195
      B41; Band 4.1 homologues
      cd13194
      Location:189 → 285
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:336 → 566
      ERM; Ezrin/radixin/moesin family

    2. XM_038652106.1 → XP_038508034.1  moesin isoform X2

      Conserved Domains (3) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13194
      Location:200 → 296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:347 → 577
      ERM; Ezrin/radixin/moesin family

    3. XM_038652105.1 → XP_038508033.1  moesin isoform X1

      Conserved Domains (3) summary
      smart00295
      Location:22 → 221
      B41; Band 4.1 homologues
      cd13194
      Location:215 → 311
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:362 → 592
      ERM; Ezrin/radixin/moesin family

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      50900835..50967356
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038587583.1 → XP_038443511.1  moesin isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:1 → 195
      B41; Band 4.1 homologues
      cd13194
      Location:189 → 285
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:336 → 566
      ERM; Ezrin/radixin/moesin family

    2. XM_038587582.1 → XP_038443510.1  moesin isoform X2

      UniProtKB/TrEMBL
      A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13194
      Location:200 → 296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:347 → 577
      ERM; Ezrin/radixin/moesin family

    3. XM_038587581.1 → XP_038443509.1  moesin isoform X1

      UniProtKB/TrEMBL
      A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
      Conserved Domains (3) summary
      smart00295
      Location:22 → 221
      B41; Band 4.1 homologues
      cd13194
      Location:215 → 311
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:362 → 592
      ERM; Ezrin/radixin/moesin family

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      41546746..41613249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014111741.3 → XP_013967216.1  moesin isoform X3

      UniProtKB/TrEMBL
      A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:1 → 195
      B41; Band 4.1 homologues
      cd13194
      Location:189 → 285
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:336 → 566
      ERM; Ezrin/radixin/moesin family

    2. XM_843243.6 → XP_848336.1  moesin isoform X2

      UniProtKB/TrEMBL
      A0A8C0KVN7, A0A8C0Z3D7, A0A8I3Q023, A0A8P0TCK5
      Conserved Domains (3) summary
      smart00295
      Location:7 → 206
      B41; Band 4.1 homologues
      cd13194
      Location:200 → 296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:347 → 577
      ERM; Ezrin/radixin/moesin family

    3. XM_005641418.3 → XP_005641475.1  moesin isoform X1

      UniProtKB/TrEMBL
      A0A8C0NFX2, A0A8C0TCI6, A0A8I3PWU6
      Conserved Domains (3) summary
      smart00295
      Location:22 → 221
      B41; Band 4.1 homologues
      cd13194
      Location:215 → 311
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:362 → 592
      ERM; Ezrin/radixin/moesin family
    Nucleotide Protein
    Heading Accession and Version

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