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    PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor [ Canis lupus familiaris (dog) ]

    Gene ID: 491870, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PCSK1Nprovided by VGNC
    Official Full Name
    proprotein convertase subtilisin/kexin type 1 inhibitorprovided by VGNC
    Primary source
    VGNC:VGNC:44321
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PCSK1N in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (42166878..42172506, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (16406140..16411765, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (42235574..42241199, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (42153141..42158765, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (42141418..42147043, complement)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene histone deacetylase 6 Neighboring gene U6 spliceosomal RNA Neighboring gene ES cell expressed Ras Neighboring gene vesicle-associated membrane protein-associated protein A-like Neighboring gene translocase of inner mitochondrial membrane 17B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proSAAS

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      42166878..42172506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038448951.1 → XP_038304879.1  proSAAS

      Conserved Domains (1) summary
      pfam07259
      Location:34 → 260
      ProSAAS; ProSAAS precursor

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      42153141..42158765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038524943.1 → XP_038380871.1  proSAAS

      Conserved Domains (1) summary
      pfam07259
      Location:34 → 260
      ProSAAS; ProSAAS precursor

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      42141418..42147043 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038650919.1 → XP_038506847.1  proSAAS

      Conserved Domains (1) summary
      pfam07259
      Location:34 → 260
      ProSAAS; ProSAAS precursor

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      42235574..42241199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038586506.1 → XP_038442434.1  proSAAS

      UniProtKB/TrEMBL
      A0A8C0L3K9
      Conserved Domains (1) summary
      pfam07259
      Location:34 → 260
      ProSAAS; ProSAAS precursor

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      16406140..16411765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_548989.7 → XP_548989.3  proSAAS

      UniProtKB/TrEMBL
      A0A8C0L3K9
      Conserved Domains (1) summary
      pfam07259
      Location:34 → 260
      ProSAAS; ProSAAS precursor
    Nucleotide Protein
    Heading Accession and Version

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