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    ZBTB1 zinc finger and BTB domain containing 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 490731, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ZBTB1provided by VGNC
    Official Full Name
    zinc finger and BTB domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:48519
    See related
    Ensembl:ENSCAFG00845002174
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ZBTB1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (39155081..39180556)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (38625165..38650702)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (39208582..39234081)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (38776929..38802424)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (38848165..38873674)

    Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene A-kinase anchoring protein 5 Neighboring gene zinc finger and BTB domain containing 25 Neighboring gene uncharacterized LOC111097075 Neighboring gene heat shock protein family A (Hsp70) member 2 Neighboring gene protein phosphatase 1 regulatory subunit 36

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel locus for dilated cardiomyopathy maps to canine chromosome 8. Werner P, et al. Genomics, 2008 Jun. PMID 18442891, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123330.1 → NP_001116802.1  zinc finger and BTB domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001116802.1

      Status: PROVISIONAL

      Source sequence(s)
      EU541625
      UniProtKB/TrEMBL
      A0A8C0NU80, A0A8I3RQH9, A0A8P0TPC1, B2CPZ7
      Related
      ENSCAFP00845003049.1, ENSCAFT00845003827.1
      Conserved Domains (2) summary
      sd00017
      Location:535 → 573
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00651
      Location:14 → 109
      BTB; BTB/POZ domain

    2. NM_001123331.1 → NP_001116803.1  zinc finger and BTB domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001116803.1

      Status: PROVISIONAL

      Source sequence(s)
      EU541626
      UniProtKB/TrEMBL
      A0A8C0QEA0, A0A8C0QWN5, A0A8I3RQH9, A0A8P0TPC1, B2CPZ8
      Related
      ENSCAFP00845003036.1, ENSCAFT00845003814.1
      Conserved Domains (3) summary
      sd00017
      Location:579 → 599
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:687 → 708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18192
      Location:3 → 116
      BTB_POZ_ZBTB1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 1 (ZBTB1)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051812.1 Reference ROS_Cfam_1.0

      Range
      39155081..39180556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038672917.1 → XP_038528845.1  zinc finger and BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QEA0, A0A8C0QWN5, A0A8I3RQH9, A0A8P0TPC1, B2CPZ8
      Conserved Domains (3) summary
      sd00017
      Location:579 → 599
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:687 → 708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18192
      Location:3 → 116
      BTB_POZ_ZBTB1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 1 (ZBTB1)

    2. XM_038672916.1 → XP_038528844.1  zinc finger and BTB domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0QEA0, A0A8C0QWN5, A0A8I3RQH9, A0A8P0TPC1, B2CPZ8
      Conserved Domains (3) summary
      sd00017
      Location:579 → 599
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:687 → 708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18192
      Location:3 → 116
      BTB_POZ_ZBTB1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 1 (ZBTB1)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049268.1 Alternate UMICH_Zoey_3.1

      Range
      38776929..38802424
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

      Range
      38848165..38873674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

      Range
      39208582..39234081
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      38625165..38650702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials