FRMD6 FERM domain containing 6 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: FRMD6provided by VGNC
Official Full Name: FERM domain containing 6provided by VGNC
Primary source: VGNC:VGNC:40983
See related: Ensembl:ENSCAFG00845003527
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	8	NC_051812.1 (27934649..28166956)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	8	NC_006590.4 (27509615..27742043)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	8	NC_049229.1 (28012258..28244423)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	8	NC_049268.1 (27604816..27836513)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	8	NC_049749.1 (27664576..27897009)

Chromosome 8 - NC_051812.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Report a willin(FRMD6)/Par3-aPKC-ROCK pathway that controls epithelial apical morphology.
Title: Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in positive regulation of hippo signaling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasmic side of apical plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: FERM domain-containing protein 6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051812.1 Reference ROS_Cfam_1.0

Range

27934649..28166956

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038673631.1 → XP_038529559.1 FERM domain-containing protein 6 isoform X1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038673630.1 → XP_038529558.1 FERM domain-containing protein 6 isoform X1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Related

ENSCAFP00845005025.1, ENSCAFT00845006327.1

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038673632.1 → XP_038529560.1 FERM domain-containing protein 6 isoform X2

UniProtKB/TrEMBL

A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4

Related

ENSCAFP00845004992.1, ENSCAFT00845006287.1

Conserved Domains (3) summary

smart00295
Location:20 → 226

B41; Band 4.1 homologues

cd13185
Location:219 → 327

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd17198
Location:15 → 112

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UMICH_Zoey_3.1

Genomic

NC_049268.1 Alternate UMICH_Zoey_3.1

Range

27604816..27836513

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038483259.1 → XP_038339187.1 FERM domain-containing protein 6 isoform X1

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038483257.1 → XP_038339185.1 FERM domain-containing protein 6 isoform X1

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038483260.1 → XP_038339188.1 FERM domain-containing protein 6 isoform X2

Conserved Domains (3) summary

smart00295
Location:20 → 226

B41; Band 4.1 homologues

cd13185
Location:219 → 327

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd17198
Location:15 → 112

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049749.1 Alternate UNSW_CanFamBas_1.0

Range

27664576..27897009

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038608829.1 → XP_038464757.1 FERM domain-containing protein 6 isoform X1

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038608828.1 → XP_038464756.1 FERM domain-containing protein 6 isoform X1

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038608830.1 → XP_038464758.1 FERM domain-containing protein 6 isoform X2

Conserved Domains (3) summary

smart00295
Location:20 → 226

B41; Band 4.1 homologues

cd13185
Location:219 → 327

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd17198
Location:15 → 112

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049229.1 Alternate UU_Cfam_GSD_1.0

Range

28012258..28244423

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038544706.1 → XP_038400634.1 FERM domain-containing protein 6 isoform X1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038544705.1 → XP_038400633.1 FERM domain-containing protein 6 isoform X1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_038544707.1 → XP_038400635.1 FERM domain-containing protein 6 isoform X2

UniProtKB/TrEMBL

A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4

Conserved Domains (3) summary

smart00295
Location:20 → 226

B41; Band 4.1 homologues

cd13185
Location:219 → 327

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd17198
Location:15 → 112

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

27509615..27742043

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_022422002.2 → XP_022277710.1 FERM domain-containing protein 6 isoform X1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_005623395.4 → XP_005623452.1 FERM domain-containing protein 6 isoform X1

See identical proteins and their annotated locations for XP_005623452.1

UniProtKB/TrEMBL

A0A8C0RCM4, A0A8I3MPY8, A0A8P0TSZ4

Conserved Domains (3) summary

cd13185
Location:227 → 335

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd14473
Location:128 → 226

FERM_B-lobe; FERM domain B-lobe

cd17198
Location:15 → 120

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)
XM_858957.6 → XP_864050.1 FERM domain-containing protein 6 isoform X2

UniProtKB/TrEMBL

A0A8I3MPX7, A0A8I3MPY8, A0A8P0NG58, A0A8P0TSZ4

Conserved Domains (3) summary

smart00295
Location:20 → 226

B41; Band 4.1 homologues

cd13185
Location:219 → 327

FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins

cd17198
Location:15 → 112

FERM_F1_FRMD6; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 6 (FRMD6)