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    LRCH4 leucine rich repeats and calponin homology domain containing 4 [ Canis lupus familiaris (dog) ]

    Gene ID: 489836, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LRCH4provided by VGNC
    Official Full Name
    leucine rich repeats and calponin homology domain containing 4provided by VGNC
    Primary source
    VGNC:VGNC:42759
    See related
    Ensembl:ENSCAFG00845001581
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LRCH4 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (9036627..9048043)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 6 NC_006588.4 (10806833..10818240)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (9049047..9060456)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (8889127..8899777)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (8866811..8878214)

    Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene procollagen C-endopeptidase enhancer Neighboring gene uncharacterized LOC119872146 Neighboring gene F-box protein 24 Neighboring gene Sin3A associated protein 25 Neighboring gene insulin receptor substrate 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat and calponin homology domain-containing protein 4; LOW QUALITY PROTEIN: leucine-rich repeat and calponin homology domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051810.1 Reference ROS_Cfam_1.0

      Range
      9036627..9048043
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038668036.1 → XP_038523964.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SK48, A0A8I3MHY6
      Related
      ENSCAFP00845002178.1, ENSCAFT00845002750.1
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:515 → 622
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    2. XM_038668035.1 → XP_038523963.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NYR7, A0A8I3MJD2, A0A8P0NRA3
      Related
      ENSCAFP00845002169.1, ENSCAFT00845002739.1
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:543 → 650
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    3. XM_038668037.1 → XP_038523965.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8I3RRL9, A0A8P0SIQ0
      Related
      ENSCAFP00845002232.1, ENSCAFT00845002808.1
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21205
      Location:546 → 657
      CH_LRCH; calponin homology (CH) domain found in the leucine-rich repeat and calponin homology domain-containing protein family

    4. XM_038668039.1 → XP_038523967.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    5. XM_038668040.1 → XP_038523968.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    6. XM_038668038.1 → XP_038523966.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:3 → 184
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:22 → 44
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:472 → 579
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049266.1 Alternate UMICH_Zoey_3.1

      Range
      8889127..8899777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038477989.1 → XP_038333917.1  LOW QUALITY PROTEIN: leucine-rich repeat and calponin homology domain-containing protein 4 isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

      Range
      8866811..8878214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038603331.1 → XP_038459259.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2

      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:515 → 622
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    2. XM_038603330.1 → XP_038459258.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X1

      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:543 → 650
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    3. XM_038603332.1 → XP_038459260.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X3

    4. XM_038603334.1 → XP_038459262.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    5. XM_038603335.1 → XP_038459263.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    6. XM_038603333.1 → XP_038459261.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X4

      Conserved Domains (3) summary
      COG4886
      Location:3 → 184
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:22 → 44
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:472 → 579
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

      Range
      9049047..9060456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038539251.1 → XP_038395179.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SK48, A0A8I3MHY6
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:515 → 622
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    2. XM_038539250.1 → XP_038395178.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NYR7, A0A8I3MJD2, A0A8P0NRA3
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:543 → 650
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    3. XM_038539252.1 → XP_038395180.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8I3RRL9, A0A8P0SIQ0
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21205
      Location:546 → 657
      CH_LRCH; calponin homology (CH) domain found in the leucine-rich repeat and calponin homology domain-containing protein family

    4. XM_038539254.1 → XP_038395182.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    5. XM_038539255.1 → XP_038395183.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    6. XM_038539253.1 → XP_038395181.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:3 → 184
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:22 → 44
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:472 → 579
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      10806833..10818240
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038538359.1 → XP_038394287.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X2

      UniProtKB/TrEMBL
      A0A8C0SK48, A0A8P0P5J8
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:515 → 622
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    2. XM_546954.8 → XP_546954.6  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A8C0KMC8, A0A8C0NYR7, A0A8P0NRA3, A0A8P0NSX3
      Conserved Domains (3) summary
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:543 → 650
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    3. XM_014114211.3 → XP_013969686.1  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      A0A8C0RPU0, A0A8P0SIQ0
      Conserved Domains (3) summary
      smart00033
      Location:551 → 658
      CH; Calponin homology domain
      COG4886
      Location:74 → 255
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:46 → 69
      LRR_RI; leucine-rich repeat [structural motif]

    4. XM_022419640.2 → XP_022275348.2  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    5. XM_022419641.2 → XP_022275349.2  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X5

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:9 → 162
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:54 → 76
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:459 → 566
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4

    6. XM_014114212.3 → XP_013969687.2  leucine-rich repeat and calponin homology domain-containing protein 4 isoform X4

      UniProtKB/TrEMBL
      A0A8P0PNI2
      Conserved Domains (3) summary
      COG4886
      Location:3 → 184
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:22 → 44
      LRR_RI; leucine-rich repeat [structural motif]
      cd21273
      Location:472 → 579
      CH_LRCH4; calponin homology (CH) domain found in leucine-rich repeat and calponin homology domain-containing protein 4
    Nucleotide Protein
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