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    ELAC2 elaC ribonuclease Z 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 489511, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ELAC2provided by VGNC
    Official Full Name
    elaC ribonuclease Z 2provided by VGNC
    Primary source
    VGNC:VGNC:40296
    See related
    Ensembl:ENSCAFG00845003879
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ELAC2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (37066393..37087109, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (37101388..37122087, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (37176497..37197209, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (37039350..37060058, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (36986550..37007239, complement)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102155247 Neighboring gene myocardin Neighboring gene Rho GTPase activating protein 44 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC102155885 Neighboring gene uncharacterized LOC111095898

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-tRNA processing endoribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial tRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc phosphodiesterase ELAC protein 2
    Names
    elaC homolog 2
    XP_022274301.2
    XP_022274302.2
    XP_038331663.1
    XP_038331664.1
    XP_038331665.1
    XP_038392846.1
    XP_038392847.1
    XP_038392848.1
    XP_038456992.1
    XP_038456993.1
    XP_038456994.1
    XP_038521564.1
    XP_038521565.1
    XP_038521566.1
    XP_546630.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      37066393..37087109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665637.1 → XP_038521565.1  zinc phosphodiesterase ELAC protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Conserved Domains (2) summary
      cd07718
      Location:475 → 678
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain

    2. XM_038665636.1 → XP_038521564.1  zinc phosphodiesterase ELAC protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Related
      ENSCAFP00845005657.1, ENSCAFT00845007093.1
      Conserved Domains (3) summary
      cd07718
      Location:475 → 680
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain
      cl23716
      Location:648 → 722
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain

    3. XM_038665638.1 → XP_038521566.1  zinc phosphodiesterase ELAC protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Related
      ENSCAFP00845005583.1, ENSCAFT00845007000.1
      Conserved Domains (3) summary
      cd07718
      Location:475 → 680
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain
      cl23716
      Location:648 → 722
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      37039350..37060058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475736.1 → XP_038331664.1  zinc phosphodiesterase ELAC protein 2 isoform X2

    2. XM_038475735.1 → XP_038331663.1  zinc phosphodiesterase ELAC protein 2 isoform X1

    3. XM_038475737.1 → XP_038331665.1  zinc phosphodiesterase ELAC protein 2 isoform X3

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      36986550..37007239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038601065.1 → XP_038456993.1  zinc phosphodiesterase ELAC protein 2 isoform X2

    2. XM_038601064.1 → XP_038456992.1  zinc phosphodiesterase ELAC protein 2 isoform X1

    3. XM_038601066.1 → XP_038456994.1  zinc phosphodiesterase ELAC protein 2 isoform X3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      37176497..37197209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536919.1 → XP_038392847.1  zinc phosphodiesterase ELAC protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4

    2. XM_038536918.1 → XP_038392846.1  zinc phosphodiesterase ELAC protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4

    3. XM_038536920.1 → XP_038392848.1  zinc phosphodiesterase ELAC protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0M1X0, A0A8I3MNJ8, A0A8P0P4K4

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      37101388..37122087 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022418594.2 → XP_022274302.2  zinc phosphodiesterase ELAC protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Conserved Domains (2) summary
      cd07718
      Location:475 → 678
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain

    2. XM_022418593.2 → XP_022274301.2  zinc phosphodiesterase ELAC protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Conserved Domains (3) summary
      cd07718
      Location:475 → 680
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain
      cl23716
      Location:648 → 722
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain

    3. XM_546630.7 → XP_546630.3  zinc phosphodiesterase ELAC protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I3MNJ8, A0A8P0P4K4
      Conserved Domains (3) summary
      cd07718
      Location:475 → 680
      RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold; Ribonuclease Z ELAC1, C-terminus of ELAC2, and related proteins; MBL-fold metallo-hydrolase domain
      cd16296
      Location:56 → 303
      RNaseZ_ELAC2-N-term-like_MBL-fold; Ribonuclease Z, N-terminus of human ELAC2 and related proteins; MBL-fold metallo-hydrolase domain
      cl23716
      Location:648 → 722
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
    Nucleotide Protein
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