ADRA2C adrenoceptor alpha 2C [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ADRA2Cprovided by VGNC
Official Full Name: adrenoceptor alpha 2Cprovided by VGNC
Primary source: VGNC:VGNC:111875
See related: Ensembl:ENSCAFG00845010654
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	3	NC_051807.1 (61121798..61123799, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	3	NC_006585.4 (63296546..63298547, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	3	NC_049224.1 (61177369..61179380, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	3	NC_049263.1 (60615963..60617962, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	3	NC_049744.1 (60821563..60823566, complement)

Chromosome 3 - NC_051807.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables alpha2-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alpha-2C adrenergic receptor; LOW QUALITY PROTEIN: alpha-2C adrenergic receptor

Names: adrenergic, alpha-2C-, receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051807.1 Reference ROS_Cfam_1.0

Range

61121798..61123799 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038661675.1 → XP_038517603.1 alpha-2C adrenergic receptor

UniProtKB/TrEMBL

A0A8C0KLK8, A0A8C0M5D3, A0A8I3NHV8

Related

ENSCAFP00845014649.1, ENSCAFT00845018764.1

Conserved Domains (2) summary

cd14964
Location:91 → 117

7tm_GPCRs; TM helix 2 [structural motif]

cl28897
Location:65 → 465

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UMICH_Zoey_3.1

Genomic

NC_049263.1 Alternate UMICH_Zoey_3.1

Range

60615963..60617962 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038472202.1 → XP_038328130.1 alpha-2C adrenergic receptor

Conserved Domains (2) summary

cd14964
Location:91 → 117

7tm_GPCRs; TM helix 2 [structural motif]

cl28897
Location:65 → 465

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049744.1 Alternate UNSW_CanFamBas_1.0

Range

60821563..60823566 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038597495.1 → XP_038453423.1 LOW QUALITY PROTEIN: alpha-2C adrenergic receptor

Conserved Domains (2) summary

cd14964
Location:91 → 117

7tm_GPCRs; TM helix 2 [structural motif]

cl28897
Location:65 → 465

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049224.1 Alternate UU_Cfam_GSD_1.0

Range

61177369..61179380 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038533165.1 → XP_038389093.1 alpha-2C adrenergic receptor

UniProtKB/TrEMBL

A0A8C0M5D3

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

63296546..63298547 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_545911.6 → XP_545911.3 LOW QUALITY PROTEIN: alpha-2C adrenergic receptor

UniProtKB/TrEMBL

A0A8C0M5D3

Conserved Domains (1) summary

cd15323
Location:57 → 465

7tmA_alpha2C_AR; alpha-2 adrenergic receptors subtype C, member of the class A family of seven-transmembrane G protein-coupled receptors