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    ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 488722, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ST8SIA2provided by VGNC
    Official Full Name
    ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2provided by VGNC
    Primary source
    VGNC:VGNC:46865
    See related
    Ensembl:ENSCAFG00845002820
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ST8SIA2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (48001090..48073258, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (50295210..50356703, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (48085662..48147171, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (47521309..47582785, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (47753561..47815049, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102156964 Neighboring gene SH2B adapter protein 1-like Neighboring gene uncharacterized LOC111095209 Neighboring gene uncharacterized LOC119870950 Neighboring gene tubulin alpha-1A chain-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes. Harduin-Lepers A, et al. BMC Evol Biol, 2008 Sep 23. PMID 18811928, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-glycan processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2,8-sialyltransferase 8B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097548.1 → NP_001091017.1  alpha-2,8-sialyltransferase 8B precursor

      See identical proteins and their annotated locations for NP_001091017.1

      Status: PROVISIONAL

      Source sequence(s)
      AM422132
      UniProtKB/TrEMBL
      A0A8C0M473, A2BCP3
      Related
      ENSCAFP00845004002.1, ENSCAFT00845005021.1
      Conserved Domains (1) summary
      pfam00777
      Location:66 → 325
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      48001090..48073258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038660480.1 → XP_038516408.1  alpha-2,8-sialyltransferase 8B isoform X1

      UniProtKB/TrEMBL
      A0A8C0L6F9, A0A8C0TVT6, A0A8I3N3C9
      Related
      ENSCAFP00845003989.1, ENSCAFT00845005005.1
      Conserved Domains (1) summary
      pfam00777
      Location:109 → 368
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RNA

    1. XR_005423845.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      47521309..47582785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      47753561..47815049 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      48085662..48147171 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      50295210..50356703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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