U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TIGIT T cell immunoreceptor with Ig and ITIM domains [ Canis lupus familiaris (dog) ]

    Gene ID: 487986, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TIGITprovided by VGNC
    Official Full Name
    T cell immunoreceptor with Ig and ITIM domainsprovided by VGNC
    Primary source
    VGNC:VGNC:47374
    See related
    Ensembl:ENSCAFG00845015083
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    VSIG9; VSTM3
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TIGIT in Genome Data Viewer
    Location:
    chromosome: 33
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (18731173..18746925)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (18592840..18608590)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (19131089..19146839)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (18538986..18554739)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (18585866..18601612)

    Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867331 Neighboring gene coiled-coil domain containing 191 Neighboring gene queuine tRNA-ribosyltransferase accessory subunit 2 Neighboring gene dopamine receptor D3 Neighboring gene microRNA mir-568 Neighboring gene zinc finger and BTB domain containing 20 Neighboring gene uncharacterized LOC119867333

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of interleukin-12 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interleukin-10 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    T-cell immunoreceptor with Ig and ITIM domains
    Names
    V-set and immunoglobulin domain containing 9
    V-set and transmembrane domain containing 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051837.1 Reference ROS_Cfam_1.0

      Range
      18731173..18746925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038444991.1 → XP_038300919.1  T-cell immunoreceptor with Ig and ITIM domains isoform X2

      UniProtKB/TrEMBL
      A0A8I3NVR5, A0A8P0NCS9
      Related
      ENSCAFP00845021238.1, ENSCAFT00845026985.1
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    2. XM_038444990.1 → XP_038300918.1  T-cell immunoreceptor with Ig and ITIM domains isoform X1

      UniProtKB/TrEMBL
      A0A8C0PIX7, A0A8I3P4F3
      Related
      ENSCAFP00845021224.1, ENSCAFT00845026964.1
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    RNA

    1. XR_005306357.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049293.1 Alternate UMICH_Zoey_3.1

      Range
      18538986..18554739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038519281.1 → XP_038375209.1  T-cell immunoreceptor with Ig and ITIM domains isoform X2

      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    2. XM_038519280.1 → XP_038375208.1  T-cell immunoreceptor with Ig and ITIM domains isoform X1

      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    RNA

    1. XR_005349432.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

      Range
      18585866..18601612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038647284.1 → XP_038503212.1  T-cell immunoreceptor with Ig and ITIM domains isoform X2

      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    2. XM_038647283.1 → XP_038503211.1  T-cell immunoreceptor with Ig and ITIM domains isoform X1

      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    RNA

    1. XR_005417020.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

      Range
      19131089..19146839
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038582868.1 → XP_038438796.1  T-cell immunoreceptor with Ig and ITIM domains isoform X2

      UniProtKB/TrEMBL
      A0A8I3NVR5, A0A8P0NCS9
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    2. XM_038582867.1 → XP_038438795.1  T-cell immunoreceptor with Ig and ITIM domains isoform X1

      UniProtKB/TrEMBL
      A0A8C0PIX7, A0A8I3P4F3
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    RNA

    1. XR_005383336.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      18592840..18608590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038462635.1 → XP_038318563.1  T-cell immunoreceptor with Ig and ITIM domains isoform X2

      UniProtKB/TrEMBL
      A0A8I3NVR5, A0A8P0NCS9
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    2. XM_005639508.4 → XP_005639565.2  T-cell immunoreceptor with Ig and ITIM domains isoform X1

      UniProtKB/TrEMBL
      A0A8C0PIX7, A0A8I3P4F3
      Conserved Domains (2) summary
      cd00096
      Location:96 → 100
      Ig; Ig strand A [structural motif]
      cl11960
      Location:96 → 197
      Ig; Immunoglobulin domain

    RNA

    1. XR_002622376.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials