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    SPINT1 serine peptidase inhibitor, Kunitz type 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 487501, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPINT1provided by VGNC
    Official Full Name
    serine peptidase inhibitor, Kunitz type 1provided by VGNC
    Primary source
    VGNC:VGNC:46746
    See related
    Ensembl:ENSCAFG00845029015
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SPINT1 in Genome Data Viewer
    Location:
    chromosome: 30
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 30 NC_051834.1 (8104320..8117280)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 30 NC_006612.4 (8030789..8043874)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 30 NC_049251.1 (8264088..8277146)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 30 NC_049290.1 (8026984..8039921)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 30 NC_049771.1 (8134558..8147504)

    Chromosome 30 - NC_051834.1Genomic Context describing neighboring genes Neighboring gene zinc finger FYVE-type containing 19 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14D Neighboring gene ras homolog family member V Neighboring gene VPS18 core subunit of CORVET and HOPS complexes

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kunitz-type protease inhibitor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051834.1 Reference ROS_Cfam_1.0

      Range
      8104320..8117280
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038442004.1 → XP_038297932.1  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Related
      ENSCAFP00845040265.1, ENSCAFT00845051330.1
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    2. XM_038442005.1 → XP_038297933.1  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049290.1 Alternate UMICH_Zoey_3.1

      Range
      8026984..8039921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038516494.1 → XP_038372422.1  kunitz-type protease inhibitor 1

      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    2. XM_038516495.1 → XP_038372423.1  kunitz-type protease inhibitor 1

      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049771.1 Alternate UNSW_CanFamBas_1.0

      Range
      8134558..8147504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038644366.1 → XP_038500294.1  kunitz-type protease inhibitor 1

      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    2. XM_038644367.1 → XP_038500295.1  kunitz-type protease inhibitor 1

      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049251.1 Alternate UU_Cfam_GSD_1.0

      Range
      8264088..8277146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038580085.1 → XP_038436013.1  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    2. XM_038580086.1 → XP_038436014.1  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006612.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      8030789..8043874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038461521.1 → XP_038317449.1  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain

    2. XM_544625.6 → XP_544625.5  kunitz-type protease inhibitor 1

      UniProtKB/TrEMBL
      A0A8C0JZY3, A0A8C0TZ26, A0A8I3PYU2
      Conserved Domains (3) summary
      smart00192
      Location:305 → 337
      LDLa; Low-density lipoprotein receptor domain class A
      pfam00014
      Location:362 → 413
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam07502
      Location:35 → 126
      MANEC; MANEC domain
    Nucleotide Protein
    Heading Accession and Version

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