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    IRX5 iroquois homeobox 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 487276, updated on 17-Aug-2024

    Summary

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    Official Symbol
    IRX5provided by VGNC
    Official Full Name
    iroquois homeobox 5provided by VGNC
    Primary source
    VGNC:VGNC:52139
    See related
    Ensembl:ENSCAFG00845001045
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See IRX5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 2 NC_051806.1 (61516686..61520066, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 2 NC_006584.4 (57609385..57612765, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 2 NC_049223.1 (60245608..60248977, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 2 NC_049262.1 (58341971..58345349, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 2 NC_049743.1 (59367066..59370437, complement)

    Chromosome 2 - NC_051806.1Genomic Context describing neighboring genes Neighboring gene iroquois homeobox 6 Neighboring gene uncharacterized LOC111092788 Neighboring gene uncharacterized LOC102154600 Neighboring gene uncharacterized LOC111092789 Neighboring gene uncharacterized LOC119870321 Neighboring gene uncharacterized LOC102155218

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    iroquois-class homeodomain protein IRX-5
    Names
    iroquois homeobox protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051806.1 Reference ROS_Cfam_1.0

      Range
      61516686..61520066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038659328.1 → XP_038515256.1  iroquois-class homeodomain protein IRX-5

      UniProtKB/TrEMBL
      A0A8C0JRE6, A0A8I3MH94, A0A8I3MN35, A0A8P0NBN8, A0A8P0P4E9
      Related
      ENSCAFP00845001429.1, ENSCAFT00845001815.1
      Conserved Domains (2) summary
      smart00548
      Location:327 → 344
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:131 → 170
      Homeobox_KN; Homeobox KN domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049262.1 Alternate UMICH_Zoey_3.1

      Range
      58341971..58345349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038470199.1 → XP_038326127.1  iroquois-class homeodomain protein IRX-5

      Conserved Domains (2) summary
      smart00548
      Location:327 → 344
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:131 → 170
      Homeobox_KN; Homeobox KN domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049743.1 Alternate UNSW_CanFamBas_1.0

      Range
      59367066..59370437 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038595240.1 → XP_038451168.1  iroquois-class homeodomain protein IRX-5

      Conserved Domains (2) summary
      smart00548
      Location:327 → 344
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:131 → 170
      Homeobox_KN; Homeobox KN domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049223.1 Alternate UU_Cfam_GSD_1.0

      Range
      60245608..60248977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038531021.1 → XP_038386949.1  iroquois-class homeodomain protein IRX-5

      UniProtKB/TrEMBL
      A0A8C0JRE6, A0A8I3MH94, A0A8I3MN35, A0A8P0NBN8, A0A8P0P4E9
      Conserved Domains (2) summary
      smart00548
      Location:327 → 344
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:131 → 170
      Homeobox_KN; Homeobox KN domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006584.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      57609385..57612765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_846105.5 → XP_851198.1  iroquois-class homeodomain protein IRX-5

      UniProtKB/TrEMBL
      A0A8C0JRE6, A0A8I3MH94, A0A8I3MN35, A0A8P0NBN8, A0A8P0P4E9
      Conserved Domains (2) summary
      smart00548
      Location:327 → 344
      IRO; Motif in Iroquois-class homeodomain proteins (only). Unknown function
      pfam05920
      Location:131 → 170
      Homeobox_KN; Homeobox KN domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials