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    KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 485197, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KCNE3provided by VGNC
    Official Full Name
    potassium voltage-gated channel subfamily E regulatory subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:42242
    See related
    Ensembl:ENSCAFG00845006390
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KCNE3 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (24063194..24076168)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (23625823..23638780)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (23975487..23988456)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (23860571..23873532)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (24057896..24070858)

    Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta 3, accessory subunit Neighboring gene uncharacterized LOC111091531 Neighboring gene lipoyl(octanoyl) transferase 2 Neighboring gene uncharacterized LOC111091533 Neighboring gene phosphoglucomutase 2 like 1 Neighboring gene U6 spliceosomal RNA Neighboring gene prolyl 4-hydroxylase subunit alpha 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane repolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of heart rate by cardiac conduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ventricular cardiac muscle cell membrane repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ventricular cardiac muscle cell action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    potassium voltage-gated channel subfamily E member 3
    Names
    potassium voltage-gated channel, Isk-related family, member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051825.1 Reference ROS_Cfam_1.0

      Range
      24063194..24076168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038430114.1 → XP_038286042.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    2. XM_038430111.1 → XP_038286039.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_038430113.1 → XP_038286041.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_038430110.1 → XP_038286038.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Related
      ENSCAFP00845008850.1, ENSCAFT00845011335.1
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_038430112.1 → XP_038286040.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049281.1 Alternate UMICH_Zoey_3.1

      Range
      23860571..23873532
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038505489.1 → XP_038361417.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    2. XM_038505486.1 → XP_038361414.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_038505488.1 → XP_038361416.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_038505484.1 → XP_038361412.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_038505487.1 → XP_038361415.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    6. XM_038505485.1 → XP_038361413.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

      Range
      24057896..24070858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038632822.1 → XP_038488750.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    2. XM_038632819.1 → XP_038488747.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_038632821.1 → XP_038488749.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_038632817.1 → XP_038488745.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_038632820.1 → XP_038488748.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    6. XM_038632818.1 → XP_038488746.1  potassium voltage-gated channel subfamily E member 3

      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

      Range
      23975487..23988456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038568649.1 → XP_038424577.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    2. XM_038568646.1 → XP_038424574.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_038568648.1 → XP_038424576.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_038568645.1 → XP_038424573.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_038568647.1 → XP_038424575.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      23625823..23638780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022407691.2 → XP_022263399.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    2. XM_014122823.3 → XP_013978298.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    3. XM_014122821.3 → XP_013978296.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_014122818.3 → XP_013978293.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_014122820.3 → XP_013978295.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    6. XM_022407690.2 → XP_022263398.1  potassium voltage-gated channel subfamily E member 3

      UniProtKB/TrEMBL
      A0A8C0JKK2, A0A8C0T3Q1, A0A8I3MYQ7
      Conserved Domains (1) summary
      pfam02060
      Location:22 → 92
      ISK_Channel; Slow voltage-gated potassium channel
    Nucleotide Protein
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