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    KCNN1 potassium calcium-activated channel subfamily N member 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 484829, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KCNN1provided by VGNC
    Official Full Name
    potassium calcium-activated channel subfamily N member 1provided by VGNC
    Primary source
    VGNC:VGNC:42284
    See related
    Ensembl:ENSCAFG00845024279
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KCNN1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (45424541..45455928, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (44852263..44883423, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (45347879..45379261, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (44661785..44685096, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (45071928..45103070, complement)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein G-like Neighboring gene arrestin domain containing 2 Neighboring gene coiled-coil domain containing 124 Neighboring gene uncharacterized LOC119864715 Neighboring gene 40S ribosomal protein S15a-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog. Qi XY, et al. Circulation, 2014 Jan 28. PMID 24190961
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small conductance calcium-activated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small conductance calcium-activated potassium channel protein 1; LOW QUALITY PROTEIN: small conductance calcium-activated potassium channel protein 1
    Names
    potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      45424541..45455928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038428198.1 → XP_038284126.1  small conductance calcium-activated potassium channel protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:355 → 433
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 171
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:259 → 341
      Ion_trans_2; Ion channel

    2. XM_038428193.1 → XP_038284121.1  small conductance calcium-activated potassium channel protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    3. XM_038428191.1 → XP_038284119.1  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    4. XM_038428196.1 → XP_038284124.1  small conductance calcium-activated potassium channel protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PHB1, A0A8P0T2I9
      Related
      ENSCAFP00845033726.1, ENSCAFT00845043015.1
      Conserved Domains (3) summary
      smart01053
      Location:384 → 459
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    5. XM_038428194.1 → XP_038284122.1  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PM30, A0A8P0T412
      Related
      ENSCAFP00845033650.1, ENSCAFT00845042930.1
      Conserved Domains (3) summary
      smart01053
      Location:384 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    6. XM_038428199.1 → XP_038284127.1  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PM30, A0A8P0T412
      Conserved Domains (3) summary
      smart01053
      Location:384 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    7. XM_038428192.1 → XP_038284120.1  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    8. XM_038428195.1 → XP_038284123.1  small conductance calcium-activated potassium channel protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    9. XM_038428197.1 → XP_038284125.1  small conductance calcium-activated potassium channel protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      44661785..44685096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038503851.1 → XP_038359779.1  LOW QUALITY PROTEIN: small conductance calcium-activated potassium channel protein 1 isoform X8

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      45071928..45103070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038631021.1 → XP_038486949.1  small conductance calcium-activated potassium channel protein 1 isoform X7

    2. XM_038631016.1 → XP_038486944.1  small conductance calcium-activated potassium channel protein 1 isoform X2

    3. XM_038631014.1 → XP_038486942.1  small conductance calcium-activated potassium channel protein 1 isoform X1

    4. XM_038631019.1 → XP_038486947.1  small conductance calcium-activated potassium channel protein 1 isoform X5

    5. XM_038631017.1 → XP_038486945.1  small conductance calcium-activated potassium channel protein 1 isoform X3

    6. XM_038631022.1 → XP_038486950.1  small conductance calcium-activated potassium channel protein 1 isoform X3

    7. XM_038631015.1 → XP_038486943.1  small conductance calcium-activated potassium channel protein 1 isoform X1

    8. XM_038631018.1 → XP_038486946.1  small conductance calcium-activated potassium channel protein 1 isoform X4

      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    9. XM_038631020.1 → XP_038486948.1  small conductance calcium-activated potassium channel protein 1 isoform X6

      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      45347879..45379261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038566868.1 → XP_038422796.1  small conductance calcium-activated potassium channel protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0YT13

    2. XM_038566863.1 → XP_038422791.1  small conductance calcium-activated potassium channel protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0YT13

    3. XM_038566861.1 → XP_038422789.1  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0YT13

    4. XM_038566866.1 → XP_038422794.1  small conductance calcium-activated potassium channel protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0KCT3, A0A8C0YT13

    5. XM_038566864.1 → XP_038422792.1  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0YT13

    6. XM_038566869.1 → XP_038422797.1  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0YT13

    7. XM_038566862.1 → XP_038422790.1  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0YT13

    8. XM_038566865.1 → XP_038422793.1  small conductance calcium-activated potassium channel protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    9. XM_038566867.1 → XP_038422795.1  small conductance calcium-activated potassium channel protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      44852263..44883423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038455614.1 → XP_038311542.1  small conductance calcium-activated potassium channel protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:355 → 433
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 171
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:259 → 341
      Ion_trans_2; Ion channel

    2. XM_038455608.1 → XP_038311536.1  small conductance calcium-activated potassium channel protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    3. XM_005632714.4 → XP_005632771.1  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    4. XM_038455612.1 → XP_038311540.1  small conductance calcium-activated potassium channel protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PHB1, A0A8P0T2I9
      Conserved Domains (3) summary
      smart01053
      Location:384 → 459
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    5. XM_038455610.1 → XP_038311538.1  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PM30, A0A8P0T412
      Conserved Domains (3) summary
      smart01053
      Location:384 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    6. XM_541945.7 → XP_541945.5  small conductance calcium-activated potassium channel protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0NXX0, A0A8I3PM30, A0A8P0T412
      Conserved Domains (3) summary
      smart01053
      Location:384 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 370
      Ion_trans_2; Ion channel

    7. XM_005632711.4 → XP_005632768.2  small conductance calcium-activated potassium channel protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0NXX0
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    8. XM_038455611.1 → XP_038311539.1  small conductance calcium-activated potassium channel protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 465
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel

    9. XM_038455613.1 → XP_038311541.1  small conductance calcium-activated potassium channel protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8C0YT13
      Conserved Domains (3) summary
      smart01053
      Location:387 → 462
      CaMBD; Calmodulin binding domain
      pfam03530
      Location:96 → 203
      SK_channel; Calcium-activated SK potassium channel
      pfam07885
      Location:291 → 373
      Ion_trans_2; Ion channel
    Nucleotide Protein
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