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    SLC6A1 solute carrier family 6 member 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 484655, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLC6A1provided by VGNC
    Official Full Name
    solute carrier family 6 member 1provided by VGNC
    Primary source
    VGNC:VGNC:46453
    See related
    Ensembl:ENSCAFG00845006668
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SLC6A1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (7371107..7413167, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (7376561..7418616, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (7415545..7457611, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (7087370..7129439, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (7443566..7485634, complement)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene histamine receptor H1 Neighboring gene uncharacterized LOC102151123 Neighboring gene uncharacterized LOC111091425 Neighboring gene uncharacterized LOC119864633 Neighboring gene uncharacterized LOC111091239 Neighboring gene solute carrier family 6 member 11 Neighboring gene uncharacterized LOC111091426

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [GAT-1 and GAD65 mRNA expressions in different brain regions in dogs at brain propofol uptake equilibrium]. Yang J, et al. Nan Fang Yi Ke Da Xue Xue Bao, 2012 Oct. PMID 23076187

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables gamma-aminobutyric acid:sodium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sodium- and chloride-dependent GABA transporter 1
    Names
    solute carrier family 6 (neurotransmitter transporter, GABA), member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      7371107..7413167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038426923.1 → XP_038282851.1  sodium- and chloride-dependent GABA transporter 1

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Related
      ENSCAFP00845009270.1, ENSCAFT00845011880.1
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    2. XM_038426924.1 → XP_038282852.1  sodium- and chloride-dependent GABA transporter 1

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      7087370..7129439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038502717.1 → XP_038358645.1  sodium- and chloride-dependent GABA transporter 1

      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    2. XM_038502718.1 → XP_038358646.1  sodium- and chloride-dependent GABA transporter 1

      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      7443566..7485634 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038629771.1 → XP_038485699.1  sodium- and chloride-dependent GABA transporter 1

      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    2. XM_038629772.1 → XP_038485700.1  sodium- and chloride-dependent GABA transporter 1

      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      7415545..7457611 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038565636.1 → XP_038421564.1  sodium- and chloride-dependent GABA transporter 1

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    2. XM_038565637.1 → XP_038421565.1  sodium- and chloride-dependent GABA transporter 1

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      7376561..7418616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_541770.6 → XP_541770.2  sodium- and chloride-dependent GABA transporter 1

      See identical proteins and their annotated locations for XP_541770.2

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

    2. XM_022406364.2 → XP_022262072.1  sodium- and chloride-dependent GABA transporter 1

      UniProtKB/TrEMBL
      A0A8C0MJH1, A0A8I3N6A1, A0A8P0N7P9
      Conserved Domains (1) summary
      cd11506
      Location:2 → 599
      SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain
    Nucleotide Protein
    Heading Accession and Version

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