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    PRKD2 protein kinase D2 [ Canis lupus familiaris (dog) ]

    Gene ID: 484427, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PRKD2provided by VGNC
    Official Full Name
    protein kinase D2provided by VGNC
    Primary source
    VGNC:VGNC:44987
    See related
    Ensembl:ENSCAFG00845003382
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PRKD2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (109732886..109767802)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (108686213..108721121)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (109912894..109947820)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (109410008..109444923)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (109044199..109079115)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 1 member 5 Neighboring gene fukutin related protein Neighboring gene striatin 4 Neighboring gene U6 spliceosomal RNA Neighboring gene dishevelled binding antagonist of beta catenin 3 Neighboring gene G protein subunit gamma 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase D2
    XP_005616468.1
    XP_005616469.1
    XP_038323697.1
    XP_038323698.1
    XP_038384417.1
    XP_038384418.1
    XP_038448698.1
    XP_038448699.1
    XP_038512498.1
    XP_038512499.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      109732886..109767802
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038656570.1 → XP_038512498.1  serine/threonine-protein kinase D2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0JLY4, A0A8C0RE79, A0A8I3MQ74
      Related
      ENSCAFP00845004782.1, ENSCAFT00845006019.1
      Conserved Domains (4) summary
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20840
      Location:129 → 201
      C1_PKD2_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cd20843
      Location:254 → 331
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    2. XM_038656571.1 → XP_038512499.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (3) summary
      cd01239
      Location:242 → 362
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:398 → 657
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:105 → 182
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      109410008..109444923
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038467769.1 → XP_038323697.1  serine/threonine-protein kinase D2 isoform X1

      Conserved Domains (4) summary
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20840
      Location:129 → 201
      C1_PKD2_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cd20843
      Location:254 → 331
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    2. XM_038467770.1 → XP_038323698.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (3) summary
      cd01239
      Location:242 → 362
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:398 → 657
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:105 → 182
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      109044199..109079115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038592770.1 → XP_038448698.1  serine/threonine-protein kinase D2 isoform X1

      Conserved Domains (4) summary
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20840
      Location:129 → 201
      C1_PKD2_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cd20843
      Location:254 → 331
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    2. XM_038592771.1 → XP_038448699.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (3) summary
      cd01239
      Location:242 → 362
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:398 → 657
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:105 → 182
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      109912894..109947820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038528489.1 → XP_038384417.1  serine/threonine-protein kinase D2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0JLY4, A0A8C0RE79, A0A8I3MQ74
      Conserved Domains (4) summary
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20840
      Location:129 → 201
      C1_PKD2_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cd20843
      Location:254 → 331
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    2. XM_038528490.1 → XP_038384418.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (3) summary
      cd01239
      Location:242 → 362
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:398 → 657
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:105 → 182
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      108686213..108721121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005616411.4 → XP_005616468.1  serine/threonine-protein kinase D2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0JLY4, A0A8C0RE79, A0A8I3MQ74
      Conserved Domains (4) summary
      cd01239
      Location:391 → 511
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:547 → 806
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20840
      Location:129 → 201
      C1_PKD2_rpt1; first protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
      cd20843
      Location:254 → 331
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins

    2. XM_005616412.3 → XP_005616469.1  serine/threonine-protein kinase D2 isoform X2

      Conserved Domains (3) summary
      cd01239
      Location:242 → 362
      PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain
      cd14082
      Location:398 → 657
      STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D
      cd20843
      Location:105 → 182
      C1_PKD2_rpt2; second protein kinase C conserved region 1 (C1 domain) found in protein kinase D2 (PKD2) and similar proteins
    Nucleotide Protein
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