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    OTUD7B OTU deubiquitinase 7B [ Canis lupus familiaris (dog) ]

    Gene ID: 483178, updated on 17-Aug-2024

    Summary

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    Official Symbol
    OTUD7Bprovided by VGNC
    Official Full Name
    OTU deubiquitinase 7Bprovided by VGNC
    Primary source
    VGNC:VGNC:44191
    See related
    Ensembl:ENSCAFG00845012281
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See OTUD7B in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (60221922..60277210, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (58672817..58728223, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (59882202..59937666, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (59071375..59126610, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (59155099..59210354, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3b subunit 4 Neighboring gene myotubularin related protein 11 Neighboring gene 60S ribosomal protein L35a-like Neighboring gene vacuolar protein sorting 45 homolog Neighboring gene uncharacterized LOC102154731 Neighboring gene pleckstrin homology domain containing O1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables K63-linked polyubiquitin modification-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein K11-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein deubiquitination involved in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    OTU domain-containing protein 7B
    Names
    OTU domain containing 7B
    XP_005630798.1
    XP_005630799.1
    XP_005630800.1
    XP_013976165.1
    XP_038278945.1
    XP_038278946.1
    XP_038278947.1
    XP_038278948.1
    XP_038355437.1
    XP_038355438.1
    XP_038355439.1
    XP_038355440.1
    XP_038418011.1
    XP_038418012.1
    XP_038418013.1
    XP_038418014.1
    XP_038482105.1
    XP_038482106.1
    XP_038482107.1
    XP_038482108.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      60221922..60277210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038423018.1 → XP_038278946.1  OTU domain-containing protein 7B isoform X2

      UniProtKB/TrEMBL
      A0A8C0L217, A0A8C0L527, A0A8C0MDW6, A0A8I3RZA9
      Related
      ENSCAFP00845017187.1, ENSCAFT00845021850.1
      Conserved Domains (4) summary
      PLN02976
      Location:436 → 498
      PLN02976; amine oxidase
      cd14347
      Location:4 → 46
      UBA_Cezanne_like; UBA-like domain found in OTU domain-containing proteins OTU7A, OTU7B and similar proteins
      pfam01754
      Location:801 → 823
      zf-A20; A20-like zinc finger
      cl19932
      Location:189 → 359
      OTU; OTU-like cysteine protease

    2. XM_038423017.1 → XP_038278945.1  OTU domain-containing protein 7B isoform X1

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (4) summary
      PLN02976
      Location:429 → 491
      PLN02976; amine oxidase
      pfam01754
      Location:794 → 816
      zf-A20; A20-like zinc finger
      cl19932
      Location:182 → 352
      OTU; OTU-like cysteine protease
      cl21463
      Location:23 → 39
      UBA_like_SF; UBA domain-like superfamily

    3. XM_038423019.1 → XP_038278947.1  OTU domain-containing protein 7B isoform X3

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    4. XM_038423020.1 → XP_038278948.1  OTU domain-containing protein 7B isoform X3

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      59071375..59126610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038499510.1 → XP_038355438.1  OTU domain-containing protein 7B isoform X2

      Conserved Domains (4) summary
      PLN02976
      Location:436 → 498
      PLN02976; amine oxidase
      cd14347
      Location:4 → 46
      UBA_Cezanne_like; UBA-like domain found in OTU domain-containing proteins OTU7A, OTU7B and similar proteins
      pfam01754
      Location:801 → 823
      zf-A20; A20-like zinc finger
      cl19932
      Location:189 → 359
      OTU; OTU-like cysteine protease

    2. XM_038499509.1 → XP_038355437.1  OTU domain-containing protein 7B isoform X1

      Conserved Domains (4) summary
      PLN02976
      Location:429 → 491
      PLN02976; amine oxidase
      pfam01754
      Location:794 → 816
      zf-A20; A20-like zinc finger
      cl19932
      Location:182 → 352
      OTU; OTU-like cysteine protease
      cl21463
      Location:23 → 39
      UBA_like_SF; UBA domain-like superfamily

    3. XM_038499511.1 → XP_038355439.1  OTU domain-containing protein 7B isoform X3

      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    4. XM_038499512.1 → XP_038355440.1  OTU domain-containing protein 7B isoform X3

      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      59155099..59210354 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038626178.1 → XP_038482106.1  OTU domain-containing protein 7B isoform X2

      Conserved Domains (4) summary
      PLN02976
      Location:436 → 498
      PLN02976; amine oxidase
      cd14347
      Location:4 → 46
      UBA_Cezanne_like; UBA-like domain found in OTU domain-containing proteins OTU7A, OTU7B and similar proteins
      pfam01754
      Location:801 → 823
      zf-A20; A20-like zinc finger
      cl19932
      Location:189 → 359
      OTU; OTU-like cysteine protease

    2. XM_038626177.1 → XP_038482105.1  OTU domain-containing protein 7B isoform X1

      Conserved Domains (4) summary
      PLN02976
      Location:429 → 491
      PLN02976; amine oxidase
      pfam01754
      Location:794 → 816
      zf-A20; A20-like zinc finger
      cl19932
      Location:182 → 352
      OTU; OTU-like cysteine protease
      cl21463
      Location:23 → 39
      UBA_like_SF; UBA domain-like superfamily

    3. XM_038626179.1 → XP_038482107.1  OTU domain-containing protein 7B isoform X3

      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    4. XM_038626180.1 → XP_038482108.1  OTU domain-containing protein 7B isoform X3

      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      59882202..59937666 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038562084.1 → XP_038418012.1  OTU domain-containing protein 7B isoform X2

      UniProtKB/TrEMBL
      A0A8C0L217, A0A8C0L527, A0A8C0MDW6, A0A8I3RZA9
      Conserved Domains (4) summary
      PLN02976
      Location:436 → 498
      PLN02976; amine oxidase
      cd14347
      Location:4 → 46
      UBA_Cezanne_like; UBA-like domain found in OTU domain-containing proteins OTU7A, OTU7B and similar proteins
      pfam01754
      Location:801 → 823
      zf-A20; A20-like zinc finger
      cl19932
      Location:189 → 359
      OTU; OTU-like cysteine protease

    2. XM_038562083.1 → XP_038418011.1  OTU domain-containing protein 7B isoform X1

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (4) summary
      PLN02976
      Location:429 → 491
      PLN02976; amine oxidase
      pfam01754
      Location:794 → 816
      zf-A20; A20-like zinc finger
      cl19932
      Location:182 → 352
      OTU; OTU-like cysteine protease
      cl21463
      Location:23 → 39
      UBA_like_SF; UBA domain-like superfamily

    3. XM_038562085.1 → XP_038418013.1  OTU domain-containing protein 7B isoform X3

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    4. XM_038562086.1 → XP_038418014.1  OTU domain-containing protein 7B isoform X3

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (3) summary
      PLN02976
      Location:344 → 406
      PLN02976; amine oxidase
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      58672817..58728223 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005630741.4 → XP_005630798.1  OTU domain-containing protein 7B isoform X2

      See identical proteins and their annotated locations for XP_005630798.1

      UniProtKB/TrEMBL
      A0A8C0L217, A0A8P0SGI8
      Conserved Domains (3) summary
      cd14347
      Location:4 → 46
      UBA_Cezanne_like; UBA-like domain found in OTU domain-containing proteins OTU7A, OTU7B and similar proteins
      pfam01754
      Location:801 → 823
      zf-A20; A20-like zinc finger
      cl19932
      Location:189 → 359
      OTU; OTU-like cysteine protease

    2. XM_014120690.3 → XP_013976165.1  OTU domain-containing protein 7B isoform X1

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (3) summary
      pfam01754
      Location:794 → 816
      zf-A20; A20-like zinc finger
      cl19932
      Location:182 → 352
      OTU; OTU-like cysteine protease
      cl21463
      Location:23 → 39
      UBA_like_SF; UBA domain-like superfamily

    3. XM_005630742.3 → XP_005630799.1  OTU domain-containing protein 7B isoform X3

      See identical proteins and their annotated locations for XP_005630799.1

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (2) summary
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease

    4. XM_005630743.3 → XP_005630800.1  OTU domain-containing protein 7B isoform X3

      See identical proteins and their annotated locations for XP_005630800.1

      UniProtKB/TrEMBL
      A0A8C0L217
      Conserved Domains (2) summary
      pfam01754
      Location:709 → 731
      zf-A20; A20-like zinc finger
      cl19932
      Location:97 → 267
      OTU; OTU-like cysteine protease
    Nucleotide Protein
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