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    HOXA3 homeobox A3 [ Canis lupus familiaris (dog) ]

    Gene ID: 482368, updated on 17-Aug-2024

    Summary

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    Official Symbol
    HOXA3provided by VGNC
    Official Full Name
    homeobox A3provided by VGNC
    Primary source
    VGNC:VGNC:41747
    See related
    Ensembl:ENSCAFG00845011325
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See HOXA3 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (40219634..40265224, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (39711922..39757426, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (40377389..40422903, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (40333739..40379239, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (40018803..40064299, complement)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene WAS/WASL-interacting protein family member 1-like Neighboring gene homeobox A1 Neighboring gene uncharacterized LOC119866384 Neighboring gene homeobox A2 Neighboring gene uncharacterized LOC119866382 Neighboring gene homeobox A4 Neighboring gene homeobox A5 Neighboring gene uncharacterized LOC119866379 Neighboring gene homeobox A6 Neighboring gene homeobox A7 Neighboring gene homeobox A9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular origins of rapid and continuous morphological evolution. Fondon JW 3rd, et al. Proc Natl Acad Sci U S A, 2004 Dec 28. PMID 15596718, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein Hox-A3
    Names
    homeo box A3
    homeobox A2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      40219634..40265224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686781.1 → XP_038542709.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    2. XM_038686778.1 → XP_038542706.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    3. XM_038686779.1 → XP_038542707.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Related
      ENSCAFP00845015728.1, ENSCAFT00845020070.1
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    4. XM_038686780.1 → XP_038542708.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    5. XM_038686782.1 → XP_038542710.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    6. XM_038686783.1 → XP_038542711.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      40333739..40379239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494891.1 → XP_038350819.1  homeobox protein Hox-A3

    2. XM_038494887.1 → XP_038350815.1  homeobox protein Hox-A3

    3. XM_038494889.1 → XP_038350817.1  homeobox protein Hox-A3

    4. XM_038494890.1 → XP_038350818.1  homeobox protein Hox-A3

    5. XM_038494888.1 → XP_038350816.1  homeobox protein Hox-A3

    6. XM_038494892.1 → XP_038350820.1  homeobox protein Hox-A3

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      40018803..40064299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038621105.1 → XP_038477033.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    2. XM_038621101.1 → XP_038477029.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    3. XM_038621103.1 → XP_038477031.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    4. XM_038621104.1 → XP_038477032.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    5. XM_038621102.1 → XP_038477030.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    6. XM_038621106.1 → XP_038477034.1  homeobox protein Hox-A3

      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      40377389..40422903 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038557166.1 → XP_038413094.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    2. XM_038557162.1 → XP_038413090.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    3. XM_038557164.1 → XP_038413092.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    4. XM_038557165.1 → XP_038413093.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    5. XM_038557163.1 → XP_038413091.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    6. XM_038557167.1 → XP_038413095.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      39711922..39757426 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022427502.2 → XP_022283210.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    2. XM_038438094.1 → XP_038294022.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    3. XM_038438106.1 → XP_038294034.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    4. XM_014119104.3 → XP_013974579.1  homeobox protein Hox-A3

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    5. XM_859451.5 → XP_864544.1  homeobox protein Hox-A3

      See identical proteins and their annotated locations for XP_864544.1

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)

    6. XM_005628661.3 → XP_005628718.1  homeobox protein Hox-A3

      See identical proteins and their annotated locations for XP_005628718.1

      UniProtKB/TrEMBL
      A0A8C0JQL8, A0A8C0RDC5, A0A8C0S4F3, A0A8I3NKF0
      Conserved Domains (3) summary
      COG5576
      Location:137 → 309
      COG5576; Homeodomain-containing transcription factor [Transcription]
      pfam00046
      Location:196 → 249
      Homeobox; Homeobox domain
      pfam13293
      Location:377 → 440
      DUF4074; Domain of unknown function (DUF4074)
    Nucleotide Protein
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