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    LGSN lengsin, lens protein with glutamine synthetase domain [ Canis lupus familiaris (dog) ]

    Gene ID: 481862, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LGSNprovided by VGNC
    Official Full Name
    lengsin, lens protein with glutamine synthetase domainprovided by VGNC
    Primary source
    VGNC:VGNC:42656
    See related
    Ensembl:ENSCAFG00845007217
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    LGS; GLULD1
    Orthologs
    human mouse all
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    Genomic context

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    See LGSN in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (27389310..27419270, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (26761476..26792749, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (27074028..27103801, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (26894374..26924142, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (26976959..27006723, complement)

    Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene translationally-controlled tumor protein-like Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene uncharacterized LOC119874274 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamine synthetase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glutamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lengsin
    Names
    Glutamate-ammonia ligase domain-containing protein 1
    glutamate-ammonia ligase (glutamine synthase) domain containing 1
    glutamate-ammonia ligase (glutamine synthetase) domain containing 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048103.1 → NP_001041568.1  lengsin

      See identical proteins and their annotated locations for NP_001041568.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ415892
      UniProtKB/Swiss-Prot
      Q1ZZS1
      UniProtKB/TrEMBL
      A0A8P0NPK3
      Related
      ENSCAFP00845010011.1, ENSCAFT00845012846.1
      Conserved Domains (3) summary
      COG0174
      Location:141 → 571
      GlnA; Glutamine synthetase [Amino acid transport and metabolism]
      pfam00120
      Location:248 → 572
      Gln-synt_C; Glutamine synthetase, catalytic domain
      pfam03951
      Location:151 → 236
      Gln-synt_N; Glutamine synthetase, beta-Grasp domain

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051816.1 Reference ROS_Cfam_1.0

      Range
      27389310..27419270 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038682766.1 → XP_038538694.1  lengsin isoform X1

      UniProtKB/TrEMBL
      A0A8I3NGW9
      Related
      ENSCAFP00845010038.1, ENSCAFT00845012883.1
      Conserved Domains (2) summary
      pfam00120
      Location:270 → 594
      Gln-synt_C; Glutamine synthetase, catalytic domain
      pfam03951
      Location:173 → 258
      Gln-synt_N; Glutamine synthetase, beta-Grasp domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049272.1 Alternate UMICH_Zoey_3.1

      Range
      26894374..26924142 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

      Range
      26976959..27006723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

      Range
      27074028..27103801 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      26761476..26792749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1ZZS1.1 GenPept UniProtKB/Swiss-Prot:Q1ZZS1

    Gene LinkOut

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