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    GRM6 glutamate metabotropic receptor 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 481452, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRM6provided by VGNC
    Official Full Name
    glutamate metabotropic receptor 6provided by VGNC
    Primary source
    VGNC:VGNC:41513
    See related
    Ensembl:ENSCAFG00845009049
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See GRM6 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (2554140..2575871)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (2701951..2723668)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (2844699..2866420)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (2525443..2547158)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (2603862..2625566)

    Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 2 Neighboring gene uncharacterized LOC111097978 Neighboring gene zinc finger protein 879 Neighboring gene zinc finger protein 354B Neighboring gene zinc finger protein 454 Neighboring gene uncharacterized LOC119876789

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables adenylate cyclase inhibiting G protein-coupled glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled glutamate receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metabotropic glutamate receptor 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051815.1 Reference ROS_Cfam_1.0

      Range
      2554140..2575871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038681149.1 → XP_038537077.1  metabotropic glutamate receptor 6

      UniProtKB/TrEMBL
      A0A8C0MAN6, A0A8C0QUS1, A0A8I3RWJ1
      Related
      ENSCAFP00845012430.1, ENSCAFT00845015980.1
      Conserved Domains (3) summary
      cd15453
      Location:585 → 857
      7tmC_mGluR6; metabotropic glutamate receptor 6 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:46 → 507
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:515 → 565
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049271.1 Alternate UMICH_Zoey_3.1

      Range
      2525443..2547158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038489753.1 → XP_038345681.1  metabotropic glutamate receptor 6

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

      Range
      2603862..2625566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038615661.1 → XP_038471589.1  metabotropic glutamate receptor 6

      Conserved Domains (3) summary
      cd15453
      Location:585 → 857
      7tmC_mGluR6; metabotropic glutamate receptor 6 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:46 → 507
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:515 → 565
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

      Range
      2844699..2866420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038551774.1 → XP_038407702.1  metabotropic glutamate receptor 6

      UniProtKB/TrEMBL
      A0A8C0MAN6, A0A8C0QUS1, A0A8I3RWJ1
      Conserved Domains (3) summary
      cd15453
      Location:585 → 857
      7tmC_mGluR6; metabotropic glutamate receptor 6 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:46 → 507
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:515 → 565
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      2701951..2723668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_538573.6 → XP_538573.3  metabotropic glutamate receptor 6

      UniProtKB/TrEMBL
      A0A8C0MAN6, A0A8C0QUS1, A0A8I3RWJ1
      Conserved Domains (3) summary
      cd15453
      Location:585 → 857
      7tmC_mGluR6; metabotropic glutamate receptor 6 in group 3, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06376
      Location:46 → 507
      PBP1_mGluR_groupIII; ligand-binding domain of the group III metabotropic glutamate receptor
      pfam07562
      Location:515 → 565
      NCD3G; Nine Cysteines Domain of family 3 GPCR
    Nucleotide Protein
    Heading Accession and Version

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