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    PORCN porcupine O-acyltransferase [ Canis lupus familiaris (dog) ]

    Gene ID: 480903, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PORCNprovided by VGNC
    Official Full Name
    porcupine O-acyltransferaseprovided by VGNC
    Primary source
    VGNC:VGNC:44821
    See related
    Ensembl:ENSCAFG00845030766
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PORCN in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (41899285..41910059)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (16139338..16150113)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (41968061..41978839)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (41886207..41896981)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (41874498..41885274)

    Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 38 member 5 Neighboring gene FtsJ RNA 2'-O-methyltransferase 1 Neighboring gene uncharacterized LOC119868194 Neighboring gene EBP cholestenol delta-isomerase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Wnt-protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables palmitoleoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Wnt protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid modification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein palmitoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein-serine O-palmitoleoyltransferase porcupine
    Names
    porcupine homolog
    XP_003435555.1
    XP_003435557.1
    XP_005641373.1
    XP_005641374.1
    XP_022271534.1
    XP_038305871.1
    XP_038305872.1
    XP_038305873.1
    XP_038305874.1
    XP_038305875.1
    XP_038379309.1
    XP_038379310.1
    XP_038379311.1
    XP_038379312.1
    XP_038379313.1
    XP_038443277.1
    XP_038443278.1
    XP_038443279.1
    XP_038443280.1
    XP_038443281.1
    XP_038507793.1
    XP_038507794.1
    XP_038507795.1
    XP_038507796.1
    XP_038507797.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051843.1 Reference ROS_Cfam_1.0

      Range
      41899285..41910059
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038449943.1 → XP_038305871.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Related
      ENSCAFP00845043045.1, ENSCAFT00845054726.1
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    2. XM_038449947.1 → XP_038305875.1  protein-serine O-palmitoleoyltransferase porcupine isoform X4

      UniProtKB/TrEMBL
      A0A8C0R598, A0A8C0T5T0, A0A8I3QBN8
      Related
      ENSCAFP00845042975.1, ENSCAFT00845054652.1
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    3. XM_038449945.1 → XP_038305873.1  protein-serine O-palmitoleoyltransferase porcupine isoform X2

      UniProtKB/TrEMBL
      A0A8C0R587, A0A8C0R598, A0A8C0T6F4, A0A8I3Q5D5
      Related
      ENSCAFP00845043027.1, ENSCAFT00845054708.1
      Conserved Domains (1) summary
      cl00738
      Location:25 → 338
      MBOAT; membrane-bound O-acyltransferase family

    4. XM_038449946.1 → XP_038305874.1  protein-serine O-palmitoleoyltransferase porcupine isoform X3

      UniProtKB/TrEMBL
      A0A8C0LAR2, A0A8C0Z275, A0A8I3Q7P5, A0A8I3SCT8
      Related
      ENSCAFP00845042988.1, ENSCAFT00845054665.1
      Conserved Domains (1) summary
      cl00738
      Location:25 → 332
      MBOAT; membrane-bound O-acyltransferase family

    5. XM_038449944.1 → XP_038305872.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049299.1 Alternate UMICH_Zoey_3.1

      Range
      41886207..41896981
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038523381.1 → XP_038379309.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    2. XM_038523385.1 → XP_038379313.1  protein-serine O-palmitoleoyltransferase porcupine isoform X4

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    3. XM_038523383.1 → XP_038379311.1  protein-serine O-palmitoleoyltransferase porcupine isoform X2

      Conserved Domains (1) summary
      cl00738
      Location:25 → 338
      MBOAT; membrane-bound O-acyltransferase family

    4. XM_038523384.1 → XP_038379312.1  protein-serine O-palmitoleoyltransferase porcupine isoform X3

      Conserved Domains (1) summary
      cl00738
      Location:25 → 332
      MBOAT; membrane-bound O-acyltransferase family

    5. XM_038523382.1 → XP_038379310.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

      Range
      41874498..41885274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038651865.1 → XP_038507793.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    2. XM_038651869.1 → XP_038507797.1  protein-serine O-palmitoleoyltransferase porcupine isoform X4

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    3. XM_038651867.1 → XP_038507795.1  protein-serine O-palmitoleoyltransferase porcupine isoform X2

      Conserved Domains (1) summary
      cl00738
      Location:25 → 338
      MBOAT; membrane-bound O-acyltransferase family

    4. XM_038651868.1 → XP_038507796.1  protein-serine O-palmitoleoyltransferase porcupine isoform X3

      Conserved Domains (1) summary
      cl00738
      Location:25 → 332
      MBOAT; membrane-bound O-acyltransferase family

    5. XM_038651866.1 → XP_038507794.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

      Range
      41968061..41978839
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038587349.1 → XP_038443277.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    2. XM_038587353.1 → XP_038443281.1  protein-serine O-palmitoleoyltransferase porcupine isoform X4

      UniProtKB/TrEMBL
      A0A8C0R598, A0A8C0T5T0, A0A8I3QBN8
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    3. XM_038587351.1 → XP_038443279.1  protein-serine O-palmitoleoyltransferase porcupine isoform X2

      UniProtKB/TrEMBL
      A0A8C0R587, A0A8C0R598, A0A8C0T6F4, A0A8I3Q5D5
      Conserved Domains (1) summary
      cl00738
      Location:25 → 338
      MBOAT; membrane-bound O-acyltransferase family

    4. XM_038587352.1 → XP_038443280.1  protein-serine O-palmitoleoyltransferase porcupine isoform X3

      UniProtKB/TrEMBL
      A0A8C0LAR2, A0A8C0Z275, A0A8I3Q7P5, A0A8I3SCT8
      Conserved Domains (1) summary
      cl00738
      Location:25 → 332
      MBOAT; membrane-bound O-acyltransferase family

    5. XM_038587350.1 → XP_038443278.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      16139338..16150113
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003435507.5 → XP_003435555.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      See identical proteins and their annotated locations for XP_003435555.1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    2. XM_005641317.4 → XP_005641374.1  protein-serine O-palmitoleoyltransferase porcupine isoform X4

      UniProtKB/TrEMBL
      A0A8C0R598, A0A8C0T5T0, A0A8I3QBN8
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family

    3. XM_022415826.2 → XP_022271534.1  protein-serine O-palmitoleoyltransferase porcupine isoform X2

      UniProtKB/TrEMBL
      A0A8C0R587, A0A8C0R598, A0A8C0T6F4, A0A8I3Q5D5
      Conserved Domains (1) summary
      cl00738
      Location:25 → 338
      MBOAT; membrane-bound O-acyltransferase family

    4. XM_003435509.5 → XP_003435557.1  protein-serine O-palmitoleoyltransferase porcupine isoform X3

      UniProtKB/TrEMBL
      A0A8C0LAR2, A0A8C0Z275, A0A8I3Q7P5, A0A8I3SCT8
      Conserved Domains (1) summary
      cl00738
      Location:25 → 332
      MBOAT; membrane-bound O-acyltransferase family

    5. XM_005641316.4 → XP_005641373.1  protein-serine O-palmitoleoyltransferase porcupine isoform X1

      See identical proteins and their annotated locations for XP_005641373.1

      UniProtKB/TrEMBL
      A0A8C0T3R8, A0A8I3Q589, A0A8I3QCY6
      Conserved Domains (1) summary
      cl00738
      Location:25 → 343
      MBOAT; membrane-bound O-acyltransferase family
    Nucleotide Protein
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