U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    DDX5 DEAD-box helicase 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 480472, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DDX5provided by VGNC
    Official Full Name
    DEAD-box helicase 5provided by VGNC
    Primary source
    VGNC:VGNC:39862
    See related
    Ensembl:ENSCAFG00845023472
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DDX5 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (13963241..13970476, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (13196543..13203768, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (14617448..14624682)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (12909346..12916580, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (14616274..14623500)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene platelet and endothelial cell adhesion molecule 1 Neighboring gene mast cell immunoglobulin like receptor 1 Neighboring gene DNA polymerase gamma 2, accessory subunit Neighboring gene centrosomal protein 95 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene karyopherin subunit alpha 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    probable ATP-dependent RNA helicase DDX5
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
    PCR product with interspecies-compatible primers
    p68 RNA helicase
    NP_001273869.1
    NP_001273870.1
    XP_038530925.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286940.2 → NP_001273869.1  probable ATP-dependent RNA helicase DDX5

      See identical proteins and their annotated locations for NP_001273869.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      JAAUVH010000313
      UniProtKB/TrEMBL
      A0A8C0LMM4, A0A8C0RLH5, A0A8I3PSN4
      Related
      ENSCAFP00845032510.1, ENSCAFT00845041458.1
      Conserved Domains (2) summary
      PTZ00110
      Location:6 → 507
      PTZ00110; helicase; Provisional
      pfam08061
      Location:498 → 532
      P68HR; P68HR (NUC004) repeat

    2. NM_001286941.1 → NP_001273870.1  probable ATP-dependent RNA helicase DDX5

      See identical proteins and their annotated locations for NP_001273870.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BM538147, BM541193, DN267719, DN342796, DN378590, GR891961
      UniProtKB/TrEMBL
      A0A8C0LMM4, A0A8C0RLH5, A0A8I3PSN4
      Conserved Domains (2) summary
      PTZ00110
      Location:6 → 507
      PTZ00110; helicase; Provisional
      pfam08061
      Location:498 → 532
      P68HR; P68HR (NUC004) repeat

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      13963241..13970476 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674997.1 → XP_038530925.1  probable ATP-dependent RNA helicase DDX5 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LMM4, A0A8C0RLH5, A0A8I3PSN4
      Conserved Domains (2) summary
      PTZ00110
      Location:6 → 507
      PTZ00110; helicase; Provisional
      pfam08061
      Location:498 → 532
      P68HR; P68HR (NUC004) repeat

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      12909346..12916580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      14616274..14623500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      14617448..14624682
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      13196543..13203768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.