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    POLR3A RNA polymerase III subunit A [ Canis lupus familiaris (dog) ]

    Gene ID: 479256, updated on 17-Aug-2024

    Summary

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    Official Symbol
    POLR3Aprovided by VGNC
    Official Full Name
    RNA polymerase III subunit Aprovided by VGNC
    Primary source
    VGNC:VGNC:44800
    See related
    Ensembl:ENSCAFG00845013802
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See POLR3A in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 4 NC_051808.1 (28135868..28184686, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 4 NC_006586.4 (27959412..28008179, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 4 NC_049225.1 (28562062..28611378, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 4 NC_049264.1 (28010348..28059559, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 4 NC_049745.1 (28209234..28258410, complement)

    Chromosome 4 - NC_051808.1Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 5 Neighboring gene uncharacterized LOC102154841 Neighboring gene U6 spliceosomal RNA Neighboring gene ribosomal protein S24

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase III subunit RPC1; LOW QUALITY PROTEIN: DNA-directed RNA polymerase III subunit RPC1
    Names
    polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
    XP_038329314.1
    XP_038329315.1
    XP_038348419.1
    XP_038390385.1
    XP_038454708.1
    XP_038454709.1
    XP_038518982.1
    XP_038518983.1
    XP_536399.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051808.1 Reference ROS_Cfam_1.0

      Range
      28135868..28184686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038663054.1 → XP_038518982.1  DNA-directed RNA polymerase III subunit RPC1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0TT29, A0A8I3NNT0, A0A8P0NH33
      Related
      ENSCAFP00845019559.1, ENSCAFT00845024864.1
      Conserved Domains (2) summary
      cd02736
      Location:1033 → 1372
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    2. XM_038663055.1 → XP_038518983.1  DNA-directed RNA polymerase III subunit RPC1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KQ58, A0A8C0TT29
      Conserved Domains (3) summary
      cd02736
      Location:1021 → 1360
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      CHL00117
      Location:841 → 1058
      rpoC2; RNA polymerase beta'' subunit; Reviewed
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049264.1 Alternate UMICH_Zoey_3.1

      Range
      28010348..28059559 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038473386.1 → XP_038329314.1  DNA-directed RNA polymerase III subunit RPC1 isoform X1

    2. XM_038473387.1 → XP_038329315.1  DNA-directed RNA polymerase III subunit RPC1 isoform X2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049745.1 Alternate UNSW_CanFamBas_1.0

      Range
      28209234..28258410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038598780.1 → XP_038454708.1  DNA-directed RNA polymerase III subunit RPC1 isoform X1

      Conserved Domains (2) summary
      cd02736
      Location:1033 → 1372
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    2. XM_038598781.1 → XP_038454709.1  DNA-directed RNA polymerase III subunit RPC1 isoform X2

      Conserved Domains (3) summary
      cd02736
      Location:1021 → 1360
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      CHL00117
      Location:841 → 1058
      rpoC2; RNA polymerase beta'' subunit; Reviewed
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049225.1 Alternate UU_Cfam_GSD_1.0

      Range
      28562062..28611378 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038534457.1 → XP_038390385.1  LOW QUALITY PROTEIN: DNA-directed RNA polymerase III subunit RPC1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KQ58, A0A8C0TT29
      Conserved Domains (3) summary
      cd02736
      Location:1021 → 1360
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      CHL00117
      Location:841 → 1058
      rpoC2; RNA polymerase beta'' subunit; Reviewed
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006586.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      27959412..28008179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038492491.1 → XP_038348419.1  DNA-directed RNA polymerase III subunit RPC1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0TT29, A0A8I3NNT0, A0A8P0NH33
      Conserved Domains (2) summary
      cd02736
      Location:1033 → 1372
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain

    2. XM_536399.7 → XP_536399.2  DNA-directed RNA polymerase III subunit RPC1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0KQ58, A0A8C0TT29
      Conserved Domains (3) summary
      cd02736
      Location:1021 → 1360
      RNAP_III_Rpc1_C; Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain
      CHL00117
      Location:841 → 1058
      rpoC2; RNA polymerase beta'' subunit; Reviewed
      cd02583
      Location:24 → 891
      RNAP_III_RPC1_N; Largest subunit (RPC1) of eukaryotic RNA polymerase III (RNAP III), N-terminal domain
    Nucleotide Protein
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