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    UCHL1 ubiquitin C-terminal hydrolase L1 [ Canis lupus familiaris (dog) ]

    Gene ID: 479098, updated on 17-Aug-2024

    Summary

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    Official Symbol
    UCHL1provided by VGNC
    Official Full Name
    ubiquitin C-terminal hydrolase L1provided by VGNC
    Primary source
    VGNC:VGNC:58342
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    UCHL-1
    Orthologs
    human mouse all
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    Genomic context

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    See UCHL1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (72157557..72171966, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (73946978..73961370, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (71972745..71987146, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (71427585..71441983, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (71589640..71604050, complement)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene janus kinase and microtubule interacting protein 1 Neighboring gene adenylyl cyclase-associated protein 1-like Neighboring gene uncharacterized LOC119871249 Neighboring gene amyloid beta precursor protein binding family B member 2 Neighboring gene uncharacterized LOC111095290 Neighboring gene heterogeneous nuclear ribonucleoprotein A3-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest. Arnaoutakis GJ, et al. J Thorac Cardiovasc Surg, 2011 Oct. PMID 21924148, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Report elevated serum UCHL1 with brain injury in a canine model of hypothermic circulatory arrest.
      Title: Serum levels of neuron-specific ubiquitin carboxyl-terminal esterase-L1 predict brain injury in a canine model of hypothermic circulatory arrest.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase isozyme L1
    XP_038328367.1
    XP_038336402.1
    XP_038389344.1
    XP_038453652.1
    XP_038517846.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      72157557..72171966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038661918.1 → XP_038517846.1  ubiquitin carboxyl-terminal hydrolase isozyme L1

      UniProtKB/TrEMBL
      A0A8C0KC77, A0A8C0LWP6, A0A8P0NHJ2
      Conserved Domains (1) summary
      cd09616
      Location:5 → 219
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      71427585..71441983 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038472439.1 → XP_038328367.1  ubiquitin carboxyl-terminal hydrolase isozyme L1

      Conserved Domains (1) summary
      cd09616
      Location:5 → 219
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      71589640..71604050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038597724.1 → XP_038453652.1  ubiquitin carboxyl-terminal hydrolase isozyme L1

      Conserved Domains (1) summary
      cd09616
      Location:5 → 219
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      71972745..71987146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038533416.1 → XP_038389344.1  ubiquitin carboxyl-terminal hydrolase isozyme L1

      UniProtKB/TrEMBL
      A0A8C0KC77, A0A8C0LWP6, A0A8P0NHJ2
      Conserved Domains (1) summary
      cd09616
      Location:5 → 219
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      73946978..73961370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038480474.1 → XP_038336402.1  ubiquitin carboxyl-terminal hydrolase isozyme L1

      UniProtKB/TrEMBL
      A0A8C0KC77, A0A8C0LWP6, A0A8P0NHJ2
      Conserved Domains (1) summary
      cd09616
      Location:5 → 219
      Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3
    Nucleotide Protein
    Heading Accession and Version

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