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    LRPAP1 LDL receptor related protein associated protein 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 479072, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LRPAP1provided by VGNC
    Official Full Name
    LDL receptor related protein associated protein 1provided by VGNC
    Primary source
    VGNC:VGNC:42780
    See related
    Ensembl:ENSCAFG00845010689
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See LRPAP1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 3 NC_051807.1 (61316241..61328837)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 3 NC_006585.4 (63491109..63503659)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 3 NC_049224.1 (61371717..61384645)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 3 NC_049263.1 (60810231..60822660)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 3 NC_049744.1 (61016034..61028737)

    Chromosome 3 - NC_051807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119871228 Neighboring gene uncharacterized LOC119871229 Neighboring gene docking protein 7 Neighboring gene HGF activator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables receptor antagonist activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables very-low-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of receptor internalization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cis-Golgi network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum-Golgi intermediate compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in rough endoplasmic reticulum lumen IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2-macroglobulin receptor-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051807.1 Reference ROS_Cfam_1.0

      Range
      61316241..61328837
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038661676.1 → XP_038517604.1  alpha-2-macroglobulin receptor-associated protein

      UniProtKB/TrEMBL
      A0A8C0M262, A0A8C0R109, A0A8I3N6H6, A0A8P0NGD3
      Related
      ENSCAFP00845014709.1, ENSCAFT00845018838.1
      Conserved Domains (3) summary
      cd14806
      Location:65 → 72
      RAP_D1; 3-helical coiled coil [structural motif]
      pfam06400
      Location:29 → 137
      Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
      pfam06401
      Location:153 → 364
      Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049263.1 Alternate UMICH_Zoey_3.1

      Range
      60810231..60822660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038472203.1 → XP_038328131.1  alpha-2-macroglobulin receptor-associated protein

      Conserved Domains (3) summary
      cd14806
      Location:65 → 72
      RAP_D1; 3-helical coiled coil [structural motif]
      pfam06400
      Location:29 → 137
      Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
      pfam06401
      Location:153 → 364
      Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049744.1 Alternate UNSW_CanFamBas_1.0

      Range
      61016034..61028737
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038597496.1 → XP_038453424.1  alpha-2-macroglobulin receptor-associated protein

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049224.1 Alternate UU_Cfam_GSD_1.0

      Range
      61371717..61384645
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038533166.1 → XP_038389094.1  alpha-2-macroglobulin receptor-associated protein

      UniProtKB/TrEMBL
      A0A8C0M262, A0A8C0R109, A0A8I3N6H6, A0A8P0NGD3
      Conserved Domains (3) summary
      cd14806
      Location:65 → 72
      RAP_D1; 3-helical coiled coil [structural motif]
      pfam06400
      Location:29 → 137
      Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
      pfam06401
      Location:153 → 364
      Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006585.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      63491109..63503659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_536218.7 → XP_536218.3  alpha-2-macroglobulin receptor-associated protein

      UniProtKB/TrEMBL
      A0A8C0M262, A0A8C0R109, A0A8I3N6H6, A0A8P0NGD3
      Conserved Domains (3) summary
      cd14806
      Location:65 → 72
      RAP_D1; 3-helical coiled coil [structural motif]
      pfam06400
      Location:29 → 137
      Alpha-2-MRAP_N; Alpha-2-macroglobulin RAP, N-terminal domain
      pfam06401
      Location:153 → 364
      Alpha-2-MRAP_C; Alpha-2-macroglobulin RAP, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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    Research Materials