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    KLF7 KLF transcription factor 7 [ Canis lupus familiaris (dog) ]

    Gene ID: 478885, updated on 17-Aug-2024

    Summary

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    Official Symbol
    KLF7provided by VGNC
    Official Full Name
    KLF transcription factor 7provided by VGNC
    Primary source
    VGNC:VGNC:54965
    See related
    Ensembl:ENSCAFG00845021900
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See KLF7 in Genome Data Viewer
    Location:
    chromosome: 37
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 37 NC_051841.1 (15452165..15543812, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 37 NC_006619.4 (16399666..16491163, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 37 NC_049258.1 (15376216..15471564, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 37 NC_049297.1 (15397928..15489697, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 37 NC_049778.1 (15371249..15462865, complement)

    Chromosome 37 - NC_051841.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111094437 Neighboring gene carboxypeptidase O Neighboring gene uncharacterized LOC119867945 Neighboring gene uncharacterized LOC111094352 Neighboring gene uncharacterized LOC102156884 Neighboring gene uncharacterized LOC111094350 Neighboring gene uncharacterized LOC119867947

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Missense Mutation in the KLF7 Gene Is a Potential Candidate Variant for Congenital Deafness in Australian Stumpy Tail Cattle Dogs. Xu F, et al. Genes (Basel), 2021 Mar 24. PMID 33805165, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A Missense Mutation in the KLF7 Gene Is a Potential Candidate Variant for Congenital Deafness in Australian Stumpy Tail Cattle Dogs.
      Title: A Missense Mutation in the KLF7 Gene Is a Potential Candidate Variant for Congenital Deafness in Australian Stumpy Tail Cattle Dogs.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Krueppel-like factor 7
    Names
    Kruppel like factor 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051841.1 Reference ROS_Cfam_1.0

      Range
      15452165..15543812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447767.1 → XP_038303695.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    2. XM_038447766.1 → XP_038303694.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    3. XM_038447768.1 → XP_038303696.1  Krueppel-like factor 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MTG6, A0A8C0R912, A0A8C0TVQ3
      Conserved Domains (3) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    4. XM_038447765.1 → XP_038303693.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Related
      ENSCAFP00845030242.1, ENSCAFT00845038627.1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    5. XM_038447769.1 → XP_038303697.1  Krueppel-like factor 7 isoform X3

      Conserved Domains (1) summary
      cd21585
      Location:2 → 152
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    RNA

    1. XR_005308379.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049297.1 Alternate UMICH_Zoey_3.1

      Range
      15397928..15489697 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521833.1 → XP_038377761.1  Krueppel-like factor 7 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    2. XM_038521832.1 → XP_038377760.1  Krueppel-like factor 7 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    3. XM_038521834.1 → XP_038377762.1  Krueppel-like factor 7 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    4. XM_038521831.1 → XP_038377759.1  Krueppel-like factor 7 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    5. XM_038521835.1 → XP_038377763.1  Krueppel-like factor 7 isoform X3

      Conserved Domains (1) summary
      cd21585
      Location:2 → 152
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    RNA

    1. XR_005351319.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049778.1 Alternate UNSW_CanFamBas_1.0

      Range
      15371249..15462865 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649940.1 → XP_038505868.1  Krueppel-like factor 7 isoform X2

    2. XM_038649939.1 → XP_038505867.1  Krueppel-like factor 7 isoform X2

    3. XM_038649938.1 → XP_038505866.1  Krueppel-like factor 7 isoform X2

    4. XM_038649941.1 → XP_038505869.1  Krueppel-like factor 7 isoform X3

      Conserved Domains (1) summary
      cd21585
      Location:2 → 152
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    RNA

    1. XR_005419033.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049258.1 Alternate UU_Cfam_GSD_1.0

      Range
      15376216..15471564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038585552.1 → XP_038441480.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    2. XM_038585551.1 → XP_038441479.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    3. XM_038585553.1 → XP_038441481.1  Krueppel-like factor 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MTG6, A0A8C0R912, A0A8C0TVQ3
      Conserved Domains (3) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    4. XM_038585549.1 → XP_038441477.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    5. XM_038585554.1 → XP_038441482.1  Krueppel-like factor 7 isoform X3

      Conserved Domains (1) summary
      cd21585
      Location:2 → 152
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    RNA

    1. XR_005385288.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006619.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      16399666..16491163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463628.1 → XP_038319556.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    2. XM_038463627.1 → XP_038319555.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    3. XM_038463629.1 → XP_038319557.1  Krueppel-like factor 7 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MTG6, A0A8C0R912, A0A8C0TVQ3
      Conserved Domains (3) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    4. XM_022415277.2 → XP_022270985.1  Krueppel-like factor 7 isoform X2

      UniProtKB/TrEMBL
      A0A8C0LQ70, A0A8C0R912, A0A8C0TVN4, A0A8C0TVQ3, A0A8I3PEF1
      Conserved Domains (4) summary
      COG5048
      Location:212 → 284
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:224 → 243
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:279 → 301
      zf-C2H2; Zinc finger, C2H2 type
      cd21585
      Location:2 → 220
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    5. XM_854989.6 → XP_860082.1  Krueppel-like factor 7 isoform X3

      Conserved Domains (1) summary
      cd21585
      Location:2 → 152
      KLF7_N; N-terminal domain of Kruppel-like factor 7

    RNA

    1. XR_005318324.1 RNA Sequence

    Nucleotide Protein
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